Immunotherapy of DC-CIK cells enhances the efficacy of chemotherapy for solid cancer: a meta-analysis of randomized controlled trials in Chinese patients

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• 作者：Xiao-peng Lan ; You-gen Chen ; Zheng Wang…
• 关键词：Solid carcinoma ; Meta ; analysis ; Dendritic cells ; Cytokine ; induced killer cells ; Immunotherapy ; R730.51 ; 瀹炰綋鑲跨槫 ; 鑽熻悆鍒嗘瀽 ; 鏍戠獊鐘剁粏鑳?/li> 缁嗚優鍥犲瓙璇卞鏉€浼ょ粏鑳?/li> 鍏嶇柅娌荤枟
• 刊名：Journal of Zhejiang University SCIENCE B
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：16
• 期：9
• 页码：743-756
• 全文大小：1,669 KB
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• 作者单位：Xiao-peng Lan (1)
  You-gen Chen (1)
  Zheng Wang (1)
  Chuan-wei Yuan (1)
  Gang-gang Wang (1)
  Guo-liang Lu (1)
  Shao-wei Mao (1)
  Xun-bo Jin (1)
  Qing-hua Xia (1)
  
  1. Minimally Invasive Urology Center, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250014, China
  
• 刊物主题：Biomedicine general;
• 出版者：Springer Berlin Heidelberg
• ISSN：1862-1783

文摘

Objective Professional antigen-presenting dendritic cells (DCs) and cytokine-induced killer (CIK) cells, components of anti-cancer therapy, have shown clinical benefits and potential to overcome chemotherapeutic resistance. To evaluate whether DC-CIK cell-based therapy improves the clinical efficacy of chemotherapy, we reviewed the literature on DC-CIK cells and meta-analyzed randomized controlled trials (RCTs).