Upregulation of Mrps18a in breast cancer identified by selecting phage antibody libraries on breast tissue sections
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- 作者：Karen Marie Juul Sørensen ; Theresa Meldgaard ; Connie Jenning Melchjorsen…
- 关键词：Phage display ; Domain antibodies ; Breast cancer ; Shadow stick selection ; Mitochondrial ribosomal protein s18a
- 刊名：BMC Cancer
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：4155KB
- 刊物主题：Cancer Research; Oncology; Surgical Oncology; Health Promotion and Disease Prevention; Biomedicine, general; Medicine/Public Health, general;
- 出版者：BioMed Central
- ISSN：1471-2407
- 卷排序：17
文摘
BackgroundOne of the hallmarks of cancer is an altered energy metabolism, and here, mitochondria play a central role. Previous studies have indicated that some mitochondrial ribosomal proteins change their expression patterns upon transformation.