Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079)

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• 作者：B. B. Y. Ma ; B. C. Goh ; W. T. Lim ; E. P. Hui ; E. H. Tan…
• 关键词：AKT inhibitor ; MK2206 ; PIK3CA ; Nasopharyngeal carcinoma
• 刊名：Investigational New Drugs
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：33
• 期：4
• 页码：985-991
• 全文大小：367 KB
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  36.Yap TA, Yan L, Patnaik A, Tunariu N, Biondo A, Fearen I, Papadopoulos KP, Olmos D, Baird R, Delgado L, Tetteh E, Beckman RA, Lupinacci L, Riisnaes R, Decordova S, Heaton SP, Swales K, deSouza NM, Leach MO, Garrett MD, Sullivan DM, de Bono JS, Tolcher AW (2014) Interrogating two schedules of the AKT inhibitor MK-2206 in patients with advanced solid tumors incorporating novel pharmacodynamic and functional imaging biomarkers. Clin Cancer Res 20(22):5672鈥?685PubMed Central PubMed View Article
  
• 作者单位：B. B. Y. Ma (1) (7)
  B. C. Goh (2)
  W. T. Lim (3)
  E. P. Hui (1)
  E. H. Tan (3)
  G. de Lima Lopes (4)
  K. W. Lo (5)
  L. Li (1)
  H. Loong (1)
  N. R. Foster (6)
  C. Erlichman (6)
  A. D. King (8)
  M. K. M. Kam (7)
  S. F. Leung (7)
  K. C. Chan (9)
  A. T. C. Chan (1)
  
  1. State Key Laboratory of Oncology in South China, Sir Y.K. Pao Centre for Cancer, Department of Clinical Oncology, Chinese University of Hong Kong, Shatin, Hong Kong SAR
  7. Department of Clinical Oncology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR
  2. National University Hospital, Cancer Science Institute of Singapore, Singapore, Singapore
  3. National Cancer Center Singapore, Investigational Medicine Unit, Singhealth, Singapore, Singapore
  4. Johns Hopkins Singapore International Medical Centre, Singapore, Singapore
  5. Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Shatin, Hong Kong SAR
  6. Mayo Clinic, Rochester, MN, USA
  8. Department of Radiology, Chinese University of Hong Kong, Shatin, Hong Kong SAR
  9. Department of Chemical Pathology, Chinese University of Hong Kong, Shatin, Hong Kong SAR
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  Pharmacology and Toxicology
  
• 出版者：Springer Netherlands
• ISSN：1573-0646

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