Psychological distress, quality of life, symptoms and unmet needs of colorectal cancer survivors near the end of treatment

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• 作者：Lahiru Russell ; Karla Gough ; Allison Drosdowsky…
• 关键词：Colorectal cancer ; Cancer survivor ; Unmet needs ; Quality of life ; Psychological distress ; End of treatment
• 刊名：Journal of Cancer Survivorship
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：9
• 期：3
• 页码：462-470
• 全文大小：183 KB
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• 作者单位：Lahiru Russell (1)
  Karla Gough (1)
  Allison Drosdowsky (1)
  Penelope Schofield (1) (2) (3)
  Sanchia Aranda (1) (2) (3)
  Phyllis N. Butow (4) (5)
  Jennifer A. Westwood (1)
  Mei Krishnasamy (1) (2) (3)
  Jane M. Young (4) (6)
  Jo Phipps-Nelson (1)
  Dorothy King (1)
  Michael Jefford (1) (2) (3) (7)
  
  1. Department of Cancer Experiences Research, Peter MacCallum Cancer Centre, East Melbourne, VIC, 3002, Australia
  2. Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, 3010, Australia
  3. Faculty of Medicine, Dentistry and Health Services, The University of Melbourne, Parkville, VIC, 3010, Australia
  4. Surgical Outcomes Research Centre, University of Sydney and Sydney South West Area Health Service, Missenden Rd, PO Box M157, Sydney, NSW, 2050, Australia
  5. Centre for Medical Psychology and Evidence-based Decision Making (CeMPED), School of Psychology, University of Sydney, A18, Sydney, NSW, 2006, Australia
  6. School of Public Health, University of Sydney, A27, Sydney, NSW, 2006, Australia
  7. Peter MacCallum Cancer Centre, Locked Bag 1, A’Beckett Street, Melbourne, VIC, 8006, Australia
  
• 刊物主题：Public Health; Oncology; Health Promotion and Disease Prevention; Health Informatics; Quality of Life Research; Primary Care Medicine;
• 出版者：Springer US
• ISSN：1932-2267

文摘

Purpose This study investigated psychological morbidity, quality of life (QoL), colorectal cancer (CRC)-specific symptoms and supportive care needs in a CRC population at the end of treatment (EOT). Methods CRC survivors (n--52) completed a post-treatment baseline questionnaire as part of a multisite supportive care randomised controlled trial (SurvivorCare). CRC survivors had completed treatment with curative intent within 0 to 6?months. Measures are as follows: Brief Symptom Inventory 18 (BSI-18) (psychological morbidity), EORTC QLQ-C30 and QLQ-CR29 (QoL and CRC-specific symptoms and problems) and Cancer Survivors-Unmet Needs (CaSUN) measure with a simplified response format (unmet needs). Linear regression models were used to compare participants-QoL with a general population sample. Correlation analysis examined associations between psychological morbidity, QoL and CRC-specific symptoms and problems. Results Average participant age was 64?years, and 51?% were male. The majority (68?%) had stage 3 disease. In comparison to population norms, CRC survivors had lower depression and anxiety scores (47.4 and 45.6, respectively) but higher somatisation, and lower role, cognitive and social functioning (p-lt;-.001). CRC survivors had higher fatigue, nausea/vomiting, appetite loss, diarrhoea and financial problems (all p-lt;-.001), as well as pain (p--.002) and constipation (p--.019). CRC-specific psychological scores were positively correlated with all three BSI domain scores, and pain and fatigue symptom scores on the QLQ-C30 while negatively correlated with all five functional scales of the QLQ-C30. Conclusions CRC survivors reported good mental health at EOT. Role and social functioning were impaired compared to population norms, possibly related to physical symptoms. Implications for Cancer Survivors Findings may help guide consultations with patients and inform the design of more tailored supportive care interventions. Trial registration: ACTRN12610000207011