Preparation of 68Ge/68Ga Generator with a Binary Ga/Ag Electrodepositions as Solid Target

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• 作者：Wu-Long Cheng ; Yun Jao ; Chung-Shin Lee and Ai-Ren Lo
• 刊名：Journal of Radioanalytical and Nuclear Chemistry
• 出版年：2000
• 出版时间：2000
• 年：2000
• 卷：245
• 期：1
• 页码：25-30
• 全文大小：233 KB

文摘

A novel type of a binary Ga/Ag alloy electrodeposited on silver substrate as a solid target was developed. It was successfully used for the preparation of 68Gc/68Ga generator. The deposition was carried out in an alkali solution containing gallium, silver and certain electrolytes at controlled current and ambient temperature so that the quality of the deposits was proved to be suited for target irradiation. The yield of 68Ge with proton bombardment on this deposits via the 69Ga(p,2n) reaction was assessed. The chemical process for providing millicuries 68Ge/68Ga generator using a generic tin dioxide as an adsorbent was also established. It was revealed from long-term elution tests that approximately 60–70 % of 68Ga could be eluted from the generator column with 4 ml of 1.0M HCl per elution, and high radio- and chemical purities of the eluates were quite satisfactory for application purposes.