Association of IL23R polymorphisms with psoriasis and psoriatic arthritis: a meta-analysis
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  • 作者:Kun-Ju Zhu (2) zhukunju1111@163.com
    Cheng-Yao Zhu (1)
    Ge Shi (1)
    Yi-Ming Fan (2) ymfan1963@163.com
  • 关键词:Psoriasis &#8211 ; Psoriatic arthritis &#8211 ; IL23R &#8211 ; Polymorphisms &#8211 ; Meta ; analysis
  • 刊名:Inflammation Research
  • 出版年:2012
  • 出版时间:October 2012
  • 年:2012
  • 卷:61
  • 期:10
  • 页码:1149-1154
  • 全文大小:247.9 KB
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    4. Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, et al. A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J Immunol. 2002;168:5699–708.
    5. Capon F, Di Meglio P, Szaub J, Prescott NJ, Dunster C, Baumber L, et al. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet. 2007;122:201–6.
    6. Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP, et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet. 2007;80:273–90.
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    22. Filer C, Ho P, Smith RL, Griffiths C, Young HS, Worthington J, et al. Investigation of association of the IL12B and IL23R genes with psoriatic arthritis. Arthritis Rheum. 2008;58:3705–9.
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  • 作者单位:1. Department of Dermatology, Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, China2. Department of Dermatology, Affiliated Hospital of Guangdong Medical College, No. 57, Remnin Avenue, Xiashan District, Zhanjiang, Guangdong 524001, China
  • ISSN:1420-908X
文摘
Background The association of variants in the IL23R gene with psoriasis and psoriatic arthritis (PsA) is a robust genetic finding

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