Eliciting 10E8-like antibodies by the membrane proximal external region peptide of HIV-1 in guinea pigs

详细信息    查看全文

• 作者：Yongjiao Yu ; Lu Fu ; Xin Gong ; Shanshan Guan ; Xiaoqiu He ; He Yin&#8230
• 关键词：Broadly ; neutralizing antibody ; HIV ; 1 vaccine ; Multiple antigen peptide ; Vaccine for HIV ; 10E8 epitope
• 刊名：Biotechnology Letters
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：39
• 期：3
• 页码：367-373
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Microbiology; Biotechnology; Applied Microbiology; Biochemistry, general;
• 出版者：Springer Netherlands
• ISSN：1573-6776
• 卷排序：39

文摘

ObjectiveTo develop an immunotherapy for HIV that can elicit 10E8-like broadly-neutralizing antibodies in guinea pigs, using a multiple antigen peptide (MAP) system as the platform and 10E8 peptide as the epitope.