Identification of immune protective genes of Eimeria maxima through cDNA expression library screening
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- 作者：XinChao Yang ; MengHui Li ; JianHua Liu ; YiHong Ji ; XiangRui Li…
- 关键词：Eimeria maxima ; cDNA expression library ; Immune protective gene
- 刊名：Parasites & Vectors
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：10
- 期：1
- 全文大小：1655KB
- 刊物主题：Parasitology; Entomology; Tropical Medicine; Infectious Diseases; Veterinary Medicine/Veterinary Science; Virology;
- 出版者：BioMed Central
- ISSN：1756-3305
- 卷排序：10
文摘
BackgroundEimeria maxima is one of the most prevalent Eimeria species causing avian coccidiosis, and results in huge economic loss to the global poultry industry. Current control strategies, such as anti-coccidial medication and live vaccines have been limited because of their drawbacks. The third generation anticoccidial vaccines including the recombinant vaccines as well as DNA vaccines have been suggested as a promising alternative strategy. To date, only a few protective antigens of E. maxima have been reported. Hence, there is an urgent need to identify novel protective antigens of E. maxima for the development of neotype anticoccidial vaccines.