Identification of target genes for spermatogenic cell-specific KRAB transcription factor ZFP819 in a male germ cell line

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• 作者：Sora Jin ; Heejin Choi ; Jun Tae Kwon ; Jihye Kim ; Juri Jeong…
• 关键词：Apoptosis ; Chromatin ; immunoprecipitation ; Germ cell ; KRAB ; Microarray ; Spermatogenesis ; Testis
• 刊名：Cell & Bioscience
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：7
• 期：1
• 全文大小：3744KB
• 刊物主题：Cell Biology; Microbiology; Stem Cells; Neurobiology; Proteomics;
• 出版者：BioMed Central
• ISSN：2045-3701
• 卷排序：7

文摘

BackgroundZfp819, a member of the Krüppel-associated box (KRAB) family, encodes a spermatogenic cell-specific transcription factor. Zfp819-overexpression induces apoptosis and inhibits proliferation in somatic cell lines.