Clinical benefits of neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreatic head: an observational study using inverse probability of treatment weighting
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- 作者：Tsutomu Fujii ; Sohei Satoi ; Suguru Yamada ; Kenta Murotani…
- 关键词：Pancreatic ductal adenocarcinoma ; Borderline resectable ; Neoadjuvant chemoradiotherapy ; Upfront surgery ; Portal vein
- 刊名：Journal of Gastroenterology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：52
- 期：1
- 页码：81-93
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Gastroenterology; Hepatology; Abdominal Surgery; Colorectal Surgery; Surgical Oncology;
- 出版者：Springer Japan
- ISSN：1435-5922
- 卷排序：52
文摘
BackgroundThe efficacy of neoadjuvant chemoradiotherapy (NACRT) and subset of pancreatic ductal adenocarcinoma (PDAC) patients who are most likely to benefit from this strategy remain elusive. The aim of this study was to investigate the effects of NACRT in patients with resectable (R) or borderline resectable (BR) adenocarcinoma of the pancreatic head. BR diseases were classified into two groups: lesions involving exclusively the portal vein system (BR-PV) and those abutting the major artery (BR-A).