Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma
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- 作者：Thomas M. Atkinson ; Jennifer L. Hay…
- 关键词：Patient ; reported outcomes ; Quality of life ; Selumetinib ; Neoplasms ; Uveal melanoma ; Adverse events ; Clinical trials
- 刊名：Journal of Cancer Research and Clinical Oncology
- 出版年：2017
- 出版时间：March 2017
- 年：2017
- 卷：143
- 期：3
- 页码：439-445
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Oncology; Cancer Research; Internal Medicine; Hematology;
- 出版者：Springer Berlin Heidelberg
- ISSN：1432-1335
- 卷排序：143
文摘
PurposeClinical trials commonly use physician-adjudicated adverse event (AE) assessment via the common terminology criteria for adverse events (CTCAE) for decision-making. Patient-reported health-related quality of life (HRQoL) data are becoming more frequent in oncology; however, the relationship between physician-adjudicated AE assessment and HRQoL is understudied.