C1–C2 spondylodiscitis in an adult with SAPHO syndrome: an unusual presentation

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• 作者：Ghita Harifi (1)
  Ahlam Belkhou (1)
  Imane El Bouchti (1)
  Meryem Ouali Idrissi (2)
  Najat Chérif Idrissi (2)
  Ahmed Ousehal (2)
  Selma El Hassani (1)
  
• 关键词：SAPHO syndrome ; Spondylodiscitis
• 刊名：Rheumatology International
• 出版年：2012
• 出版时间：February 2012
• 年：2012
• 卷：32
• 期：2
• 页码：445-447
• 全文大小：230KB
• 参考文献：1. Schilling F (2004) SAPHO syndrome, Encyclopedie Orphanet, October 2004. Available at http://www.orpha.net/data/patho/FR/fr-sapho
  2. Kotilainen P, Merilahti-Palo R, Lehtonen OP et al (1996) / Propionibacterium acnes isolated from sternal osteitis in a patient with SAPHO syndrome. J Rheumatol 23:1302-304
  3. Chamot AM, Benhamou CL, Kahn MF, Beraneck L, Kaplan G, Prost A (1987) Le syndrome acné, pustulose, hyperostose, ostéite (SAPHO). Résultats d’une enquête nationale. 85 observations. Rev Rhum 54:187-96
  4. Kasperczyk A, Freyschmidt J (1994) Pustulotic arthroosteitis: spectrum of bone lesions with palmoplantar pustulosis. Radiology 191:207-11
  5. Toussirot E, Dupond JL, Wendling D (1997) Spondylodiscitis in SAPHO syndrome. A series of eight cases. Ann Rheum Dis 56:52-8 CrossRef
  6. Nachtigal A, Cardinal E, Bureau NJ, Sainte-Marie LG, Milette F (1999) Vertebral involvement in SAPHO syndrome: MRI findings. Skeletal Radiol 28(3):163-68 CrossRef
  7. Takigawa T, Tanaka M, Nakahara S, Sugimoto Y, Ozaki T (2008) SAPHO syndrome with rapidly progressing destructive spondylitis: two cases treated surgically. Eur Spine J 17(2):S331–S337 CrossRef
  8. Laredo JD, Vuillemin-Bodaghi V, Boutry N, Cotten A, Parlier-Cuau C (2007) SAPHO syndrome: MR appearance of vertebral involvement. Radiology 242(3):825-31 CrossRef
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• 作者单位：Ghita Harifi (1)
  Ahlam Belkhou (1)
  Imane El Bouchti (1)
  Meryem Ouali Idrissi (2)
  Najat Chérif Idrissi (2)
  Ahmed Ousehal (2)
  Selma El Hassani (1)
  
  1. Service de Rhumatologie, CHU Mohamed VI, 40000, Marrakech, Morocco
  2. Service de Radiologie, CHU Mohamed VI, Marrakech, Morocco
  

文摘

The main advantage of recognition and diagnosis of SAPHO syndrome is the avoidance of unnecessary prolonged antibiotic treatment and repeated invasive procedures. The combination of synovitis, acne, pustulosis, hyperostosis and aseptic osteitis is known as SAPHO syndrome. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. Osteosclerosis of the vertebral bodies, hyperostosis, and erosions of the vertebral plates are rarely encountered. We present a case of SAPHO syndrome with C1–C2 spondylodiscitis. Diagnosis of SAPHO syndrome was established using Khan et al. criteria (Schilling, SAPHO syndrome, Encyclopedie Orphanet, 2004). CT showed osteosclerotic lesions of dens axis. MRI sequences reveal inflammatory bone marrow oedema. Radiologists should be aware of this unusual syndrome to avoid misdiagnosis (tumour/infection), unnecessary surgery, and antibiotic therapy.