High adherence to malaria treatment: promising results of an adherence study in South Kivu, Democratic Republic of the Congo
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- 作者：Sibylle Gerstl ; Alexis Namagana ; Liliana Palacios ; Franklin Mweshi…
- 关键词：Malaria ; Adherence ; Compliance ; Emergency setting ; Conflict ; Morbidity ; Mortality ; Treatment ; Artemisinin ; based combination therapy/ACT ; Democratic Republic of the Congo
- 刊名：Malaria Journal
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：14
- 期：1
- 全文大小：993 KB
- 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：1475-2875
文摘
Background In resource-poor settings, treatment adherence is a major determinant of response to anti-malarial drugs as most are taken at home without medical supervision. Evidence on adherence to artemisinin-based combination therapy (ACT) is limited. The study aimed to measure adherence and identify reasons for non-adherence to a 3-day, fixed-dose combination (FDC) of artesunate–amodiaquine (ASAQ), the first-line treatment for uncomplicated malaria in the Médecins Sans Frontières project in the Shabunda Health Zone, South Kivu, Democratic Republic of Congo, a highly malarious and conflict-affected area.