MilkAMP: a comprehensive database of antimicrobial peptides of dairy origin

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• 作者：Jérémie Théolier (1)
  Ismail Fliss (1)
  Julie Jean (1)
  Riadh Hammami (1)
  
• 关键词：MilkAMP database ; Dairy peptides ; Antimicrobial peptides ; Milk hydrolysates
• 刊名：Dairy Science & Technology
• 出版年：2014
• 出版时间：March 2014
• 年：2014
• 卷：94
• 期：2
• 页码：181-193
• 全文大小：320 KB
• 作者单位：Jérémie Théolier (1)
  Ismail Fliss (1)
  Julie Jean (1)
  Riadh Hammami (1)
  
  1. STELA Dairy Research Centre, Institute of Nutrition and Functional Foods, Université Laval, G1V 0A6, Quebec, QC, Canada
  
• ISSN：1958-5594

文摘

The number of identified and characterized bioactive peptides derived from milk proteins is increasing. Although many antimicrobial peptides of dairy origin are now well known, important structural and functional information is still missing or unavailable to potential users. The compilation of such information in one centralized resource such as a database would facilitate the study of the potential of these peptides as natural alternatives for food preservation or to help thwart antibiotic resistance in pathogenic bacteria. To achieve this goal, we established MilkAMP, a new database that contains valuable information on antimicrobial peptides of dairy origin, including microbiological and physicochemical data. The current release of MilkAMP contains 371 entries, including 9 hydrolysates, 299 antimicrobial peptides, 23 peptides predicted as antimicrobial, and 40 non-active peptides. Freely available at http://milkampdb.org/, this database should be useful to help develop uses of biologically active peptides in both the pharmaceutical and food sectors. As more information about antimicrobial peptides becomes available, the database will be expanded and improved accordingly.