Pregnant women carrying microcephaly foetuses and Zika virus contain potentially pathogenic microbes and parasites in their amniotic fluid

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• 作者：Diogo Antonio Tschoeke ; Louisi Souza de Oliveira ; Luciana Leomil…
• 关键词：Zika Virus ; Metatranscriptomics ; Microbiome ; Microchepaly
• 刊名：BMC Medical Genomics
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：10
• 期：1
• 全文大小：654KB
• 刊物主题：Human Genetics; Microarrays; Gene Expression;
• 出版者：BioMed Central
• ISSN：1755-8794
• 卷排序：10

文摘

BackgroundMicrocephaly has become a major public health problem in Brazil. The total number of newborns with microcephaly was reported to be >4000 in June 2016. Studies suggest that Zika Virus is a major cause of new microcephaly cases in Brazil. Inside the uterus, the foetus is surrounded by the Amniotic Fluid, a proximal fluid that contains foetal and maternal cells as well as microorganisms and where Zika Virus was already found.