Device Closure of Secundum Atrial Septal Defects in Infants Weighing Less Than 8?Kg

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• 作者：Ram N. Bishnoi ; Allen D. Everett ; Richard E. Ringel ; Carl Y. Owada…
• 关键词：Atrial septal defect ; Amplatzer septal occluder ; Gore Helex septal occluder
• 刊名：Pediatric Cardiology
• 出版年：2014
• 出版时间：October 2014
• 年：2014
• 卷：35
• 期：7
• 页码：1124-1131
• 全文大小：556 KB
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  9. Everett AD, Ringel R, Rhodes JF, Doyle TP, Owada CY, Holzer RJ, Cheatham JP, Ringewald J, Bandisode V, Chen YL, Lim DS (2006) Development of the MAGIC congenital heart disease catheterization database for interventional outcome studies. J Interv Cardiol 19:173-77 CrossRef
  10. Everett AD, Jennings J, Sibinga E, Owada CY, Lim DS, Cheatham JP, Holzer RJ, Ringewald J, Bandisode V, Ringel RE (2009) Community use of the Amplatzer atrial septal defect occlude: results of the multicenter MAGIC atrial septal defect study. Pediatr Cardiol 30:240-47 CrossRef
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• 作者单位：Ram N. Bishnoi (1)
  Allen D. Everett (1)
  Richard E. Ringel (1)
  Carl Y. Owada (2)
  Ralf J. Holzer (3)
  Joanne L. Chisolm (3)
  Wolfgang A. Radtke (4)
  D. Scott Lim (5)
  John F. Rhodes Jr (6)
  John D. Coulson (1)
  
  1. Division of Pediatric Cardiology, Johns Hopkins University School of Medicine, 1800 Orleans street M2328, Baltimore, MD, 21287, USA
  2. Department of Cardiology and Cardiothoracic Surgery, Children’s Hospital Central California, Madera, CA, USA
  3. Nationwide Children’s Hospital, Columbus, OH, USA
  4. Nemours Cardiac Center, Wilmington, DE, USA
  5. University of Virginia Health System, Charlottesville, VA, USA
  6. Duke University School of Medicine, Durham, NC, USA
  
• ISSN：1432-1971

文摘

This study aimed to assess the technical aspects of atrial septal defect (ASD) closure using the Amplatzer septal occluder (ASO) and the Gore Helex septal occluder (GHSO) for infants weighing less than 8?kg and to determine the safety, effectiveness, and near-to-intermediate-term outcome of the closure. The Mid-Atlantic Group of Interventional Cardiology Registry of percutaneous, transcatheter ASD closure procedures was reviewed for this analysis. Patients from 10 hospitals in the United States were included. The cohort for this report consisted of 68 patients weighing less than 8?kg (range, 2.3-.8?kg; mean, 5.5?±?1.6?kg) and ranging in age from 1 to 24?months (mean, 8.6?±?4.7?months). The indications for ASD closure were failure to thrive, significant right heart enlargement, shunts otherwise thought to be hemodynamically significant, and poor overall clinical status. Devices were successfully implanted in 66 of the 68 infants (97.1?% procedural success rate). Five minor procedure-related complications occurred. At follow-up assessment, clinical status had improved significantly as measured by improved weight gain and decreased ventilator or oxygen dependence. All residual shunts spontaneously closed during the follow-up period. Six late deaths occurred, none of which were clearly device related. The ASO and GHSO can be safely and effectively implanted for ASD closure in infants weighing less than 8?kg. These procedures usually are successful and seldom complicated, resulting in significant clinical improvement.