Antiretroviral Therapy Use, Medication Adherence, and Viral Suppression Among PLWHA with Panic Symptoms

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• 作者：Tanyka Suzanne Sam ; Heidi E. Hutton ; Bryan Lau ; Mary E. McCaul…
• 关键词：Panic symptoms ; Psychiatric disorder ; Medication adherence ; Antiretroviral therapy use ; Viral suppression
• 刊名：AIDS and Behavior
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：19
• 期：11
• 页码：2049-2056
• 全文大小：370 KB
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• 作者单位：Tanyka Suzanne Sam (1)
  Heidi E. Hutton (2)
  Bryan Lau (3)
  Mary E. McCaul (2)
  Jeanne Keruly (4)
  Richard Moore (3) (4)
  Geetanjali Chander (4)
  
  1. Department of Medicine, The Brooklyn Hospital Center, 121 Dekalb Avenue, Maynard Building, Suite 14D, Brooklyn, NY, 11201, USA
  2. Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
  3. Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
  4. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Public Health
  Health Psychology
  Infectious Diseases
  
• 出版者：Springer Netherlands
• ISSN：1573-3254

文摘

Panic symptoms are prevalent among PLWHAs, yet few studies have examined their relationship with HIV outcomes. Using data from an observational cohort study in Baltimore, MD, we examined the association between panic symptoms and antiretroviral therapy (ART) use, medication adherence, and viral suppression. Data were analyzed using generalized estimating equations and adjusted for age, sex, race/ethnicity, cocaine and/or heroin use, clinic enrollment time, alcohol use, and depressive symptoms. Between June 2010 and September 2012, 1195 individuals participated in 2080 audio computer assisted interviews; 9.9 % (n = 118) of individuals endorsed current panic symptoms. In multivariate analysis, panic symptoms were associated with decreased ART use (IRR 0.94; p = 0.05). Panic symptoms were neither associated with medication adherence nor viral suppression. These findings were independent of depressive symptoms and substance use. Panic symptoms are under-recognized in primary care settings and present an important barrier to ART use. Further studies investigating the reasons for this association are needed. Keywords Panic symptoms Psychiatric disorder Medication adherence Antiretroviral therapy use Viral suppression