Sedation in non-invasive ventilation: do we know what to do (and why)?

详细信息    查看全文

• 作者：Dan Longrois (1)
  Giorgio Conti (2)
  Jean Mantz (3)
  Andreas Faltlhauser (4)
  Riku Aantaa (5)
  Peter Tonner (6)
  
  1. Universit茅 Paris-Diderot ; H么pitaux Universitaires Paris Nord Val de Seine ; D茅partement d鈥橝nesth茅sie R茅animation Chirurgicale ; H么pital Bichat-Claude Bernard ; Paris ; France
  2. Department of Intensive Care and Anesthesiology ; Universit脿 Cattolica del Sacro Cuore ; Rome ; Italy
  3. Anesthesiology Department ; Beaujon Hospital ; AP-HP ; Universit茅 Paris-Diderot ; Paris ; France
  4. First Department of Internal Medicine ; Kliniken Nordoberpfalz AG ; Klinikum Weiden ; Weiden ; Germany
  5. Department of Anesthesiology ; Intensive Care ; Emergency Care and Pain Medicine ; University of Turku ; Turku ; Finland
  6. Department of Anesthesiology and Intensive Care Medicine ; Emergency Medicine Hospital Links der Weser GmbH ; Bremen ; Germany
  
• 关键词：Agitation ; Benzodiazepines ; Delirium ; Dexmedetomidine ; Dyspnoea ; Ketamine ; Non ; invasive ventilation ; Opioids ; Propofol ; Sedation
• 刊名：Multidisciplinary Respiratory Medicine
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：9
• 期：1
• 全文大小：607 KB
• 参考文献：1. Keenan, SP, Sinuff, T, Burns, KE, Muscedere, J, Kutsogiannis, J, Mehta, S, Cook, DJ, Ayas, N, Adhikari, NK, Hand, L, Scales, DC, Pagnotta, R, Lazosky, L, Rocker, G, Dial, S, Laupland, K, Sanders, K, Dodek, P (2011) Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting. CMAJ 183: pp. E195-E214 CrossRef
  2. Burns, KE, Meade, MO, Premji, A, Adhikari, NK (2014) Noninvasive ventilation as a weaning strategy for mechanical ventilation in adults with respiratory failure: a Cochrane systematic review. CMAJ 186: pp. E112-E122 130974" target="_blank" title="It opens in new window">CrossRef
  3. Burns, KE, Meade, MO, Premji, A, Adhikari, NK (2013) Noninvasive positive-pressure ventilation as a weaning strategy for intubated adults with respiratory failure. Cochrane Database Syst Rev.
  4. Hill, NS, Lin, D, Levy, M, O鈥橞rien, A, Klinger, J, Houtchens, J, Nelson, D, McCormick, J (2000) Noninvasive positive pressure ventilation (NPPV) to facilitate extubation after acute respiratory failure: a feasibility study [abstract]. Am J Respir Crit Care Med 161: pp. B18
  5. Nava, S, Ambrosino, N, Clini, E, Prato, M, Orlando, G, Vitacca, M, Brigada, P, Fracchia, C, Rubini, F (1998) Noninvasive mechanical ventilation in the weaning of patients with respiratory failure due to chronic obstructive pulmonary disease: a randomized, controlled trial. Ann Intern Med 128: pp. 721-728 CrossRef
  6. Prasad, SB, Chaudhry, D, Khanna, R (2009) Role of noninvasive ventilation in weaning from mechanical ventilation in patients of chronic obstructive pulmonary disease: an Indian experience. Indian J Crit Care Med 13: pp. 207-212 CrossRef
  7. Rabie Agmy, GM, Mohamed, AZ, Mohamed, RN (2004) Noninvasive ventilation in the weaning of patients with acute-on-chronic respiratory failure due to COPD. Chest 126: pp. 755
  8. Vaschetto, R, Turucz, E, Dellapiazza, F, Guido, S, Colombo, D, Cammarota, G, Della Corte, F, Antonelli, M, Navalesi, P (2012) Noninvasive ventilation after early extubation in patients recovering from hypoxemic acute respiratory failure: a single-centre feasibility study. Intensive Care Med 38: pp. 1599-1606 134-012-2652-7" target="_blank" title="It opens in new window">CrossRef
  9. Scala, R (2013) Sedation during non-invasive ventilation to treat acute respiratory failure. Shortness of Breath 2: pp. 35-43
  10. Rocker, GM, Mackenzie, MG, Williams, B, Logan, PM (1999) Noninvasive positive pressure ventilation: successful outcome in patients with acute lung injury/ARDS. Chest 115: pp. 173-177 1378/chest.115.1.173" target="_blank" title="It opens in new window">CrossRef
  11. Constantin, JM, Schneider, E, Cayot-Constantin, S, Guerin, R, Bannier, F, Futier, E, Bazin, JE (2007) Remifentanil-based sedation to treat noninvasive ventilation failure: a preliminary study. Intensive Care Med 33: pp. 82-87 134-006-0447-4" target="_blank" title="It opens in new window">CrossRef
  12. Rocco, M, Conti, G, Alessandri, E, Morelli, A, Spadetta, G, Laderchi, A, Di Santo, C, Francavilla, S, Pietropaoli, P (2010) Rescue treatment for non invasive ventilation failure due to interface intolerance with remifentanilanalgo sedation: a pilot study. Intensive Care Med 36: pp. 2060-2065 134-010-2026-y" target="_blank" title="It opens in new window">CrossRef
  13. Akada, S, Takeda, S, Yoshida, Y, Nakazato, K, Mori, M, Hongo, T, Tanaka, K, Sakamoto, A (2008) The efficacy of dexmedetomidine in patients with noninvasive ventilation: a preliminary study. Anesth Analg 107: pp. 167-170 13/ane.0b013e3181732dc2" target="_blank" title="It opens in new window">CrossRef
  14. Takasaki, Y, Kido, T, Samba, K (2009) Dexmedetomidine facilitates induction of noninvasive positive pressure ventilation for acute respiratory failure in patients with severe asthma. J Anesth 23: pp. 147-150 CrossRef
  15. Clouzeau, B, Bui, HN, Vargas, F, Grenouillet-Delacre, M, Guilhon, E, Gruson, D, Hilbert, G (2010) Target-controlled infusion of propofol for sedation in patients with non-invasive ventilation failure due to low tolerance: a preliminary study. Intensive Care Med 36: pp. 1675-1680 134-010-1904-7" target="_blank" title="It opens in new window">CrossRef
  16. Senoglu, N, Oksuz, H, Dogan, Z, Yildiz, H, Demirkiran, H, Ekerbicer, H (2010) Sedation during noninvasive mechanical ventilation with dexmedetomidine or midazolam: A randomized, double-blind, prospective study. Curr Ther Res Clin Exp 71: pp. 141-153 CrossRef
  17. Huang, Z, Chen, YS, Yang, ZL, Liu, JY (2012) Dexmedetomidine versus midazolam for the sedation of patients with non-invasive ventilation failure. Intern Med 51: pp. 2299-2305 CrossRef
  18. Devlin, JW, Nava, S, Fong, JJ, Bahhady, I, Hill, NS (2007) Survey of sedation practices during noninvasive positive-pressure ventilation to treat acute respiratory failure. Crit Care Med 35: pp. 2298-2302 CrossRef
  19. Sferrazza Papa, GF, Di Marco, F, Akoumianaki, E, Brochard, L (2012) Recent advances in interfaces for non-invasive ventilation: from bench studies to practical issues. Minerva Anestesiol 78: pp. 1146-1153
  20. Chawla, R, Sidhu, US, Kumar, V, Nagarkar, S, Brochard, L (2008) Noninvasive ventilation: a survey of practice patterns of its use in India. Indian J Crit Care Med 12: pp. 163-169 CrossRef
  21. Zhuang, PJ, Wang, X, Zhang, XF, Zhou, ZJ, Wang, Q (2011) Postoperative respiratory and analgesic effects of dexmedetomidine or morphine for adenotonsillectomy in children with obstructive sleep apnoea. Anaesthesia 66: pp. 989-993 1365-2044.2011.06817.x" target="_blank" title="It opens in new window">CrossRef
  22. Ankichetty, S, Wong, J, Chung, F (2011) A systematic review of the effects of sedatives and anesthetics in patients with obstructive sleep apnea. J Anaesthesiol Clin Pharmacol 27: pp. 447-458 CrossRef
  23. Eastwood, PR, Platt, PR, Shepherd, K, Maddison, K, Hillman, DR (2005) Collapsibility of the upper airway at different concentrations of propofolanesthesia. Anesthesiology 103: pp. 470-477 CrossRef
  24. Olofsen, E, Boom, M, Nieuwenhuijs, D, Sarton, E, Teppema, L, Aarts, L, Dahan, A (2010) Modeling the non-steady state respiratory effects of remifentanil in awake and propofol-sedated healthy volunteers. Anesthesiology 112: pp. 1382-1395 13e3181d69087" target="_blank" title="It opens in new window">CrossRef
  25. Nava, S, Ceriana, P (2004) Causes of failure of noninvasive mechanical ventilation. Respir Care 49: pp. 295-303
  26. Glossop, AJ, Shephard, N, Bryden, DC, Mills, GH (2012) Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis. Br J Anaesth 109: pp. 305-314 CrossRef
  27. Cabello, B, Thille, AW, Drouot, X, Galia, F, Mancebo, J, d鈥橭rtho, MP, Brochard, L (2008) Sleep quality in mechanically ventilated patients: comparison of three ventilatory modes. Crit Care Med 36: pp. 1749-1755 13e3181743f41" target="_blank" title="It opens in new window">CrossRef
  28. Roche Campo, F, Drouot, X, Thille, AW, Galia, F, Cabello, B, d鈥橭rtho, MP, Brochard, L (2010) Poor sleep quality is associated with late noninvasive ventilation failure in patients with acute hypercapnic respiratory failure. Crit Care Med 38: pp. 477-485 13e3181bc8243" target="_blank" title="It opens in new window">CrossRef
  29. Brown, EN, Lydic, R, Schiff, ND (2010) General anesthesia, sleep, and coma. N Engl J Med 363: pp. 2638-2650 CrossRef
  30. Bosma, K, Ferreyra, G, Ambrogio, C, Pasero, D, Mirabella, L, Braghiroli, A, Appendini, L, Mascia, L, Ranieri, VM (2007) Patient-ventilator interaction and sleep in mechanically ventilated patients: pressure support versus proportional assist ventilation. Crit Care Med 35: pp. 1048-1054 CrossRef
  31. Fanfulla, F, Taurino, AE, Lupo, ND, Trentin, R, D鈥橝mbrosio, C, Nava, S (2007) Effect of sleep on patient/ventilator asynchrony in patients undergoing chronic non-invasive mechanical ventilation. Respir Med 101: pp. 1702-1707 CrossRef
  32. Carteaux, G, Lyazidi, A, Cordoba-Izquierdo, A, Vignaux, L, Jolliet, P, Thille, AW, Richard, JC, Brochard, L (2012) Patient-ventilator asynchrony during noninvasive ventilation: a bench and clinical study. Chest 142: pp. 367-376 1378/chest.11-2279" target="_blank" title="It opens in new window">CrossRef
  33. Vignaux, L, Tassaux, D, Carteaux, G, Roeseler, J, Piquilloud, L, Brochard, L, Jolliet, P (2010) Performance of noninvasive ventilation algorithms on ICU ventilators during pressure support: a clinical study. Intensive Care Med 36: pp. 2053-2059 134-010-1994-2" target="_blank" title="It opens in new window">CrossRef
  34. Barr, J, Fraser, GL, Puntillo, K, Ely, EW, G茅linas, C, Dasta, JF, Davidson, JE, Devlin, JW, Kress, JP, Joffe, AM, Coursin, DB, Herr, DL, Tung, A, Robinson, BR, Fontaine, DK, Ramsay, MA, Riker, RR, Sessler, CN, Pun, B, Skrobik, Y, Jaeschke, R (2013) Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 41: pp. 263-306 13e3182783b72" target="_blank" title="It opens in new window">CrossRef
  35. Arpino, PA, Kalafatas, K, Thompson, BT (2008) Feasibility of dexmedetomidine in facilitating extubation in the intensive care unit. J Clin Pharm Ther 33: pp. 25-30 1365-2710.2008.00883.x" target="_blank" title="It opens in new window">CrossRef
  36. Charlesworth, M, Elliott, MW, Holmes, JD (2012) Noninvasive positive pressure ventilation for acute respiratory failure in delirious patients: understudied, underreported, or underappreciated? A systematic review and meta-analysis. Lung 190: pp. 597-603 CrossRef
  37. Nydahl, P, Ruhl, AP, Bartoszek, G, Dubb, R, Filipovic, S, Flohr, HJ, Kaltwasser, A, Mende, H, Rothaug, O, Schuchhardt, D, Schwabbauer, N, Needham, DM (2014) Early mobilization of mechanically ventilated patients: a 1-day point-prevalence study in Germany. Crit Care Med 42: pp. 1178-1186 CrossRef
  38. Schmidt, M, Demoule, A, Polito, A, Porchet, R, Aboab, J, Siami, S, Morelot-Panzini, C, Similowski, T, Sharshar, T (2011) Dyspnea in mechanically ventilated critically ill patients. Crit Care Med 39: pp. 2059-2065 13e31821e8779" target="_blank" title="It opens in new window">CrossRef
  39. Parshall, MB, Schwartzstein, RM, Adams, L, Banzett, RB, Manning, HL, Bourbeau, J, Calverley, PM, Gift, AG, Harver, A, Lareau, SC, Mahler, DA, Meek, PM, O'Donnell, DE (2012) An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea. Am J Respir Crit Care Med 185: pp. 435-452 CrossRef
  40. Banzett, RB, Mulnier, HE, Murphy, K, Rosen, SD, Wise, RJ, Adams, L (2000) Breathlessness in humans activates insular cortex. Neuroreport 11: pp. 2117-2120 CrossRef
  41. Peiffer, C, Poline, JB, Thivard, L, Aubier, M, Samson, Y (2001) Neural substrates for the perception of acutely induced dyspnea. Am J Respir Crit Care Med 163: pp. 951-957 CrossRef
  42. Evans, KC, Banzett, RB, Adams, L, McKay, L, Frackowiak, RS, Corfield, DR (2002) BOLD fMRI identifies limbic, paralimbic, and cerebellar activation during air hunger. J Neurophysiol 88: pp. 1500-1511
  43. von Leupoldt, A, Dahme, B (2005) Differentiation between the sensory and affective dimension of dyspnea during resistive load breathing in normal subjects. Chest 128: pp. 3345-3349 1378/chest.128.5.3345" target="_blank" title="It opens in new window">CrossRef
  44. von Leupoldt, A, Ambruzsova, R, Nordmeyer, S, Jeske, N, Dahme, B (2006) Sensory and affective aspects of dyspnea contribute differentially to the Borg scale's measurement of dyspnea. Respiration 73: pp. 762-768
  45. Yorke, J, Russell, AM, Swigris, J, Shuldham, C, Haigh, C, Rochnia, N, Hoyle, J, Jones, PW (2011) Assessment of dyspnea in asthma: validation of The Dyspnea-12. J Asthma 48: pp. 602-608 CrossRef
  46. Hsu, Y-W, Cortinez, LI, Robertson, KM, Keifer, JC, Sum-Ping, ST, Moretti, EW, Young, CC, Wright, DR, Macleod, DB, Somma, J (2004) Dexmedetomidine pharmacodynamics: part I. crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology 101: pp. 1066-1076 CrossRef
  47. Ho, AM-H, Chen, S, Karmakar, MK (2005) Central apnoea after balanced general anaesthesia that included dexmedetomidine. Br J Anaesth 95: pp. 773-775 CrossRef
  48. Morel, DR, Forster, A, Gemperle, M (1986) Noninvasive evaluation of breathing pattern and thoraco-abdominal motion following the infusion of ketamine or droperidol in humans. Anesthesiology 65: pp. 392-398 CrossRef
  49. Miller, AC, Jamin, CT, Elamin, EM (2011) Continuous intravenous infusion of ketamine for maintenance sedation. Minerva Anestesiol 77: pp. 812-820
  50. Parashchanka, A, Schelfout, S, Coppens, M (2014) Role of novel drugs in sedation outside the operating room: dexmedetomidine, ketamine and remifentanil. Curr Opin Anaesthesiol 27: pp. 442-447 CrossRef
  51. Jakob, SM, Ruokonen, E, Grounds, RM, Sarapohja, T, Garratt, C, Pocock, SJ, Bratty, JR, Takala, J (2012) Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA 307: pp. 1151-1160 CrossRef
  52. Devlin, JW, Al-Qadheeb, NS, Chi, A, Roberts, R, Qawi, I, Garpestad, E, Hill, NS (2014) Efficacy and safety of early dexmedetomidine during non-invasive ventilation for patients with acute respiratory failure: a randomized, double-blind, placebo-controlled, pilot study. Chest 145: pp. 1204-1212 1378/chest.13-1448" target="_blank" title="It opens in new window">CrossRef
  53. Chiumello, D, Chevallard, G, Gregoretti, C (2011) Non-invasive ventilation in postoperative patients: a systematic review. Intensive Care Med 37: pp. 918-929 134-011-2210-8" target="_blank" title="It opens in new window">CrossRef
  54. Jaber, S, Chanques, G, Jung, B (2010) Postoperative noninvasive ventilation. Anesthesiology 112: pp. 453-461 13e3181c5e5f2" target="_blank" title="It opens in new window">CrossRef
  
• 刊物主题：Pneumology/Respiratory System;
• 出版者：BioMed Central
• ISSN：2049-6958

文摘

This review examines some of the issues encountered in the use of sedation in patients receiving respiratory support from non-invasive ventilation (NIV). This is an area of critical and intensive care medicine where there are limited (if any) robust data to guide the development of best practice and where local custom appears to exert a strong influence on patterns of care. We examine aspects of sedation for NIV where the current lack of structure may be contributing to missed opportunities to improve standards of care and examine the existing sedative armamentarium. No single sedative agent is currently available that fulfils the criteria for an ideal agent but we offer some observations on the relative merits of different agents as they relate to considerations such as effects on respiratory drive and timing, and airways patency. The significance of agitation and delirium and the affective aspect(s) of dyspnoea are also considered. We outline an agenda for placing the use of sedation in NIV on a more systematic footing, including clearly expressed criteria and conditions for terminating NIV and structural and organizational conditions for prospective multicentre trials.