Sleep Disturbances in Neurodevelopmental Disorders
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  • 作者:Althea Robinson-Shelton ; Beth A. Malow
  • 关键词:Sleep disturbances ; Neurodevelopmental disorders ; Down syndrome ; Trisomy 21 ; Prader Willi syndrome ; Autism spectrum disorder ; Angelman syndrome
  • 刊名:Current Psychiatry Reports
  • 出版年:2016
  • 出版时间:January 2016
  • 年:2016
  • 卷:18
  • 期:1
  • 全文大小:323 KB
  • 参考文献:1.Sheldon SH, Ferber R, Kryger MHE, editors. Principles and practice of pediatric sleep medicine. Philadelphia: Elsevier Saunders; 2005.
    2.Johnson C. Sleep problems in children with mental retardation and autism. Child Adolesc Psychiatr Clin. 1996;5(3):673–83.
    3.Barlett LB, Rooney V, Spedding S. Nocturnal difficulties in a population of mentally handicapped children. Br J Ment Subnorm. 1985;31:54–9.
    4.Cotton S, Richdale A. Brief report: parental descriptions of sleep problems in children with autism, Down syndrome, and Prader-Willi syndrome. Res Dev Disabil. 2006;27(2):151–61.CrossRef PubMed
    5.Angriman M, Caravale B. Sleep in children with neurodevelopmental disabilities. Neuropediatrics. 2015;46:199–210.CrossRef PubMed
    6.Cotton SM, Richdale AL. Sleep patterns and behaviour in typically developing children and children with autism, Down syndrome, Prader-Willi syndrome and intellectual disability. Res Autism Spectr Disord. 2010;4(3):490–500.CrossRef
    7.Parker SE, Mai CT, Canfield MA, et al. Updated national birth prevalence estimates for selected birth defects in the United States, 2004–2006. Birth Defects Res A Clin Mol Teratol. 2010;88(12):1008–16.CrossRef PubMed
    8.Hoffmire CA, Magyar CI, Connoly HV, Fernandez ID, Van Wijngaarden E. High Prevalence of Sleep Disorders and Associated Comorbidities in a Community Sample of Children with Down Syndrome. J Clin Sleep Med. 2014;10(4):411–9.
    9.••
Breslin J, Spanò G, Bootzin R, Anand P, Nadel L, Edgin J. Obstructive sleep apnea syndrome and cognition in Down syndrome. Dev Med Child Neurol. 2014;56(7):657–64. This study shows that children with Down syndrome and untreated OSA have poorer cognitive outcome compared to Down syndrome patients without OSA. CrossRef PubMed
10.Dyken ME, Lin-Dyken DC, Poulton S, Zimmerman MB, Sedars E. Prospective polysomnographic analysis of obstructive sleep apnea in down syndrome. Arch Pediatr Adolesc Med. 2003;157(7):655–60.CrossRef PubMed
11.De Miguel-Díez J, Alvarez-Sala JL, Villa-Asensi JR. Magnetic resonance imaging of the upper airway in children with Down syndrome. Am J Respir Crit Care Med. 2002;165(8):1187.CrossRef PubMed
12.Bertrand P, Navarro H, Caussade S, Holmgren N, Sánchez I. Airway anomalies in children with Down syndrome: endoscopic findings. Pediatr Pulmonol. 2003;36(2):137–41.CrossRef PubMed
13.Cua CL, Blankenship A, North AL, Hayes J, Nelin LD. Increased incidence of idiopathic persistent pulmonary hypertension in Down syndrome neonates. Pediatr Cardiol. 2007;28(4):250–4.CrossRef PubMed
14.Levine OR et al. Alveolar hypoventilation and cor pulmonale associated with chronic airway obstruction in infants with Down syndrome. Clin Pediatr (Phila). 1982;21(1):25–9.CrossRef
15.Carskadon MA et al. Sleep-disordered breathing and behavior in three risk groups: preliminary findings from parental reports. Childs Nerv Syst. 1993;21(1):25–9.
16.Andreou G, Galanopoulou C, Gourgoulianis K, Karapetsas A, Molyvdas P. Cognitive status in Down syndrome individuals with sleep disordered breathing deficits (SDB). Brain Cogn. 2002;50(1):145–9.CrossRef PubMed
17.Bull MJ. Health supervision for children with Down syndrome. Pediatrics. 2011;128(2):393–406.CrossRef PubMed
18.Goffinski A, Stanley MA, Shepherd N, et al. Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic. Am J Med Genet A. 2015;167(2):324–30.CrossRef
19.Uliel S, Tauman R, Greenfeld M, Sivan Y. Normal polysomnographic respiratory values in children and adolescents. Chest. 2004;125(3):872–8.CrossRef PubMed
20.Traeger N, Schultz B, Pollock AN, Mason T, Marcus CL, Arens R. Polysomnographic values in children 2–9 years old: additional data and review of the literature. Pediatr Pulmonol. 2005;40(1):22–30.CrossRef PubMed
21.•
Austeng ME, Øverland B, Kværner KJ, et al. Obstructive sleep apnea in younger school children with Down syndrome. Int J Pediatr Otorhinolaryngol. 2014;78(7):1026–9. This study highlights the importance of continuing to monitor and test for OSA in children with triosomy even beyond the recommended first 5 years. CrossRef PubMed
22.Shete MM, Stocks RMS, Sebelik ME, Schoumacher RA. Effects of adeno-tonsillectomy on polysomnography patterns in Down syndrome children with obstructive sleep apnea: a comparative study with children without Down syndrome. Int J Pediatr Otorhinolaryngol. 2010;74(3):241–4.CrossRef PubMed
23.Goldstein NA, Armfield DR, Kingsley LA, Borland LM, Allen GC, Post JC. Postoperative complications after tonsillectomy and adenoidectomy in children with Down syndrome. Arch Otolaryngol Head Neck Surg. 1998;124(2):171–6.CrossRef PubMed
24.Donnelly LF, Shott SR, LaRose CR, Chini BA, Amin RS. Causes of persistent obstructive sleep apnea despite previous tonsillectomy and adenoidectomy in children with Down syndrome as depicted on static and dynamic cine MRI. Am J Roentgenol. 2004;183(1):175–81.CrossRef
25.Donaldson ME, Chu CE, Cooke A. The Prader-Willi syndrome. Arch Dis Child. 1994;70(1):58–63.
26.DE State MW. Genetics of childhood disorders: XV. Prader-Willi syndrome: genes, brain, and behavior. J Am Acad Child Adolesc Psychiatry. 2000;39(6):797–800.CrossRef PubMed
27.Holm A, Cassidy B, Whitman Y, Butler C. Prader-Willi syndrome : concensus diagnostic criteria. Pediatrics. 1993;91(2):398–402.
28.Cassidy SB, McKillop JA, Morgan W. Sleep disorders in Prader–Willi syndrome. Dysmorphol Clin Genet. 1990;4:3–17.
29.Nixon GM, Brouillette RT. Sleep and breathing in Prader-Willi syndrome. Pediatr Pulmonol. 2002;34(3):209–17.CrossRef PubMed
30.Hoyt RW, Scarpa N, Wilmott RW, Cohen A, Schwartz E. Pulmonary function abnormalities in homozygous beta-thalassemia. J Pediatr. 1986;109(3):452–5.
31.••
Sedky K, Bennett DS, Pumariega A. Prader willi syndrome and obstructive sleep apnea: co-occurrence in the pediatric population. J Clin Sleep Med. 2014;10(4):403–9. This study highlights the high prevalence of OSA in Prader-Willi syndrome and that post adenotonsillectomy PSG is important in patients with OSA. PubMedCentral PubMed
32.Cohen M, Hamilton J, Narang I. Clinically important age-related differences in sleep related disordered breathing in infants and children with Prader-Willi syndrome. PLoS ONE. 2014;9(6):e101012.
33.Arens R, Gozal D, Omlin KJ, Livingston FR, Liu J, Keens TD, et al. Hypoxic and hypercapnic ventilatory responses in Prader-Willi syndrome. J Appl Physiol. 1994;77:2224–30.PubMed
34.Kaplan J, Fredrickson PA, Richard JW. Sleep and breathing in patients with the Prader Willi syndrome. Mayo Clin Proc. 1991;66(11):1124–6.CrossRef PubMed
35.Harris JC. Is excessive daytime sleepiness characteristic of Prader Willi syndrome. Arch Pediatr Adolesc Med. 1996;150:1288–93.CrossRef PubMed
36.Manni R, Politini L, Nobili L, et al. Hypersomnia in the Prader Willi syndrome: clinical-electrophysiological features and underlying factors. Clin Neurophysiol. 2001;112(5):800–5.CrossRef PubMed
37.Camfferman D, Doug McEvoy R, O’Donoghue F, Lushington K. Prader Willi syndrome and excessive daytime sleepiness. Sleep Med Rev. 2008;12(1):65–75.CrossRef PubMed
38.McCandless SE. Clinical report—health supervision for children with Prader-Willi syndrome. Pediatrics. 2011;127(1):195–204.CrossRef PubMed
39.Spence SJ. The genetics of autism. Semin Pediatr Neurol. 2004;11(3):196–204.CrossRef PubMed
40.American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington DC: American Psychiatric Association; 2013.
41.Richdale AL, Schreck KA. Sleep problems in autism spectrum disorders: prevalence, nature, & possible biopsychosocial aetiologies. Sleep Med Rev. 2009;13(6):403–11.CrossRef PubMed
42.Allik H, Larsson J-O, Smedje H. Sleep patterns of school-age children with Asperger syndrome or high-functioning autism. J Autism Dev Disord. 2006;36(5):585–95.CrossRef PubMed
43.Souders MC, Mason TBA, Valladares O, et al. Sleep behaviors and sleep quality in children with autism spectrum disorders. Sleep. 2009;32(12):1566–78.PubMedCentral PubMed
44.Liu X, Hubbard JA, Fabes RA, Adam JB. Sleep disturbances and correlates of children with autism spectrum disorders. Child Psychiatry Hum Dev. 2006;37(2):179–91.CrossRef PubMed
45.Sivertsen B, Posserud M-B, Gillberg C, Lundervold AJ, Hysing M. Sleep problems in children with autism spectrum problems: a longitudinal population-based study. Autism. 2012;16(2):139–50.CrossRef PubMed
46.Malow BA, Marzec ML, McGrew SG, Wang L, Henderson LM, Stone WL. Characterizing sleep in children with autism spectrum disorders: a multidimensional approach. Sleep. 2006;29(12):1563–71.PubMed
47.Wiggs L, Stores G. Sleep patterns and sleep disorders in children with autistic spectrum disorders: insights using parent report and actigraphy. Dev Med Child Neurol. 2004;46(6):372–80.CrossRef PubMed
48.Goodlin-Jones B, Tang K, Liu J, Anders TF. Sleep problems, sleepiness and daytime behavior in preschool-age children. J Child Psychol Psychiatry. 2009;50(12):1532–40.CrossRef PubMed
49.Limoges É, Mottron L, Bolduc C, Berthiaume C, Godbout R. Atypical sleep architecture and the autism phenotype. Brain. 2005;128(5):1049–61.CrossRef PubMed
50.Hollway JA, Aman MG, Butter E. Correlates and risk markers for sleep disturbance in participants of the autism treatment network. J Autism Dev Disord. 2013;43(12):2830–43.CrossRef PubMed
51.Johnson KP, Malow BA. Assessment and pharmacologic treatment of sleep disturbances in autism. Child Adolesc Psychiatr Clin N Am. 2008;17(4):773–85.CrossRef PubMed
52.Malow BA MS. Sleep and autism spectrum disorders. In: Tuchman R RI, editor. Autism: a neurological disorders of early brain development. Vol London: MacKeith Press; 2006. pp 188–201.
53.Ackermann K, Stehle JH. Melatonin synthesis in the human pineal gland: advantages, implications, and difficulties. Chronobiol Int. 2006;23(1–2):369–79.CrossRef PubMed
54.Tordjman S, Anderson GM, Pichard N, Charbuy H, Touitou Y. Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. Biol Psychiatry. 2005;57(2):134–8.CrossRef PubMed
55.Bourgeron T. The possible interplay of synaptic and clock genes in autism spectrum disorders The possible interplay of synaptic and clock genes in autism spectrum disorders. 2007;LXXII (Freitag):645–654.
56.Goldman SE, Adkins KW, Calcutt MW, et al. Melatonin in children with autism spectrum disorders: endogenous and pharmacokinetic profiles in relation to sleep. J Autism Dev Disord. 2014;44(10):2525–35.PubMedCentral CrossRef PubMed
57.•
Veatch OJ, Goldman SE, Adkins KW, Malow BA. Melatonin in children with autism spectrum disorders : how does the evidence fit together. J Nat Sci. 2015;1(7):13–15. This review looks at how genetic variations in the melatonin pathway affects insomnia in ASD.
58.••Malow BA, Byars K, Johnson K, et al. A practice pathway for the identification, evaluation, and management of insomnia in children and adolescents with autism spectrum disorders. Pediatrics. 2012;130:S106–24. Expert concensus on how to identify and manage insomnia in children and adolescents with ASD.CrossRef PubMed
59.Malow BA, Adkins KW, Reynolds A, Loh A, Fawkes D, Katz T, et al. Parent-based sleep education for children with autism spectrum disorders. J Autism Dev Disord. 2014;44(1):216–28.CrossRef PubMed
60.Johnson CR, Turner KS, Foldes E, Brooks MM, Kronk R, Wiggs L. Behavioral parent training to address sleep disturbances in young children with autism spectrum disorder: a pilot trial. Sleep Med. 2013;14(10):995–1004.PubMedCentral CrossRef PubMed
61.Vriend JL, Corkum PV, Moon EC, Smith IM. Behavioral interventions for sleep problems in children with autism spectrum disorders: current findings and future directions. J Pediatr Psychol. 2011;36(9):1017–29.CrossRef PubMed
62.Guénolé F, Godbout R, Nicolas A, Franco P, Claustrat B, Baleyte JM. Melatonin for disordered sleep in individuals with autism spectrum disorders: systematic review and discussion. Sleep Med Rev. 2011;15(6):379–87.CrossRef PubMed
63.Andersen IM, Kaczmarska J, McGrew SG, Malow BA. Melatonin for insomnia in children with autism spectrum disorders. J Child Neurol. 2008;23(5):482–5.CrossRef PubMed
64.Paavonen EJ, Nieminen-von Wendt T, Vanhala R, Aronen ET, von Wendt L. Effectiveness of melatonin in the treatment of sleep disturbances in children with Asperger disorder. J Child Adolesc Psychopharmacol. 2003;13(1):83–95.CrossRef PubMed
65.Accardo JA, Malow BA. Sleep, epilepsy, and autism. Epilepsy Behav. 2014;47:202–6.CrossRef PubMed
66.Robinson AA, Malow BA. Gabapentin shows promise in treating refractory insomnia in children. J Child Neurol. 2012;28(12):1618–21.CrossRef PubMed
67.McCall C, McCall WV. What is the role of sedating antidepressants, antipsychotics, and anticonvulsants in the management of insomnia? Curr Psychiatry Rep. 2012;14(5):494–502.CrossRef PubMed
68.Williams C et al. Angelman syndrome 2005: updated consensus for diagnostic criteria. Am J Med Genet A. 2006;140A(5):413–8.CrossRef
69.Dan B, Bouillot E, Bengoetxea A, Boyd SG, Cheron G. Distinct multi-joint control strategies in spastic diplegia associated with prematurity or Angelman syndrome. Clin Neurophysiol. 2001;112(9):1618–25.CrossRef PubMed
70.Mabb A. Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes. Trends Neurosci. 2011;34(6):293–303.PubMedCentral CrossRef PubMed
71.Clayton-Smith J. Clinical research on Angelman syndrome in the United Kingdom: observations on 82 affected individuals. Am J Med Genet. 1993;46(1):12–5.CrossRef PubMed
72.Pelc K, Cheron G, Boyd SG, Dan B. Are there distinctive sleep problems in Angelman syndrome? Sleep Med. 2008;9(4):434–41.CrossRef PubMed
73.Walz NC, Beebe D, Byars K. Sleep in individuals with Angelman syndrome: parent perceptions of patterns and problems. Am J Ment Retard. 2005;110(4):243–52.CrossRef PubMed
74.Bruni O, Ferri R, D’Agostino G, Miano S, Roccella M, Elia M. Sleep disturbances in Angelman syndrome: a questionnaire study. Brain Dev. 2004;26(4):233–40.CrossRef PubMed
75.Miano S, Bruni O, Leuzzi V, Elia M, Verrillo E, Ferri R. Sleep polygraphy in Angelman syndrome. Clin Neurophysiol. 2004;115(4):938–45.CrossRef PubMed
76.Nunes ML, Ferri R, Arzimanoglou A, Curzi L, Appel CC, Costa da Costa J. Sleep organization in children with partial refractory epilepsy. J Child Neurol. 2003;18(11):763–6.CrossRef PubMed
77.Herman ST, Walczak TS, Basil CW. Distribution of partial seizures during the sleep–wake cycle: differences by seizure onset site. Neurology. 2001;56:1453–9.CrossRef PubMed
78.Minecan D, Natarajan A, Marzec M, Malow BA. Relationship of epileptic seizures to sleep stage and sleep depth. Sleep. 2002;25:899–904.PubMed
79.Malow BA. The interaction between sleep and epilepsy. Epilepsia. 2007;48(9):36–8.CrossRef PubMed
80.Conant KD, Thibert RL, Thiele EA. Epilepsy and the sleep-wake patterns found in Angelman syndrome. Epilepsia. 2009;50(11):2497–500.CrossRef PubMed
81.Huntsman MM, Porcello DM, Homanics GE, DeLorey TM, Huguenard JR. Reciprocal inhibitory connections and network synchrony in the mammalian thalamus. Science. 1999;283(5401):541–3.CrossRef PubMed
82.DeLorey TM, Handforth A, Anagnostaras SG, et al. Mice lacking the β3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome. J Neurosci. 1998;18(20):8505–14.PubMed
83.Dan B, Boyd SG. Angelman syndrome reviewed from a neurophysiological perspective. The UBE3A-GABRB3 hypothesis. Neuropediatrics. 2003;34(4):169–76.CrossRef PubMed
84.Shinnar S, Kang H, Berg AT, Goldensohn ES Hauser W, Moshe SL. EEG abnormalities in children with a first unprovoked seizure. Epilepsia. 1994;35:471–6.CrossRef PubMed
85.Walz NC, Baranek GT. Sensory processing patterns in persons with Angelman syndrome. Am J Occup Ther. 2006;60:472–9.CrossRef PubMed
86.Robinson AA, Goldman S, Barnes G, Goodpaster L, Malow BA. Electroencephalogram (EEG) duration needed to detect abnormalities in Angelman syndrome: is 1 hour of overnight recording sufficient? J Child Neurol. 2015;30(1):58–62.CrossRef PubMed
87.Valente KD, Andrade JQ, Grossmann RM, et al. Angelman syndrome: difficulties in EEG pattern recognition and possible misinterpretations. Epilepsia. 2003;44(8):1051–63.CrossRef PubMed
88.Braam W, Didden R, Smits MG, Curfs LMG. Melatonin for chronic insomnia in Angelman syndrome: a randomized placebo-controlled trial. J Child Neurol. 2008;23(6):649–54.CrossRef PubMed
89.Zhdanova IV, Wurtman RJ, Wagstaff J. Effects of low dose of melatonin on sleep in children with Angelman syndrome. Pediatr Endocrinol Metab. 1999;12:57–67.
  • 作者单位:Althea Robinson-Shelton (1)
    Beth A. Malow (1)

    1. Sleep Division, Department of Neurology A-0118 MCN, Vanderbilt University Medical Center, 1161 21st Ave. South, Nashville, TN, 37232, USA
  • 刊物主题:Psychiatry;
  • 出版者:Springer US
  • ISSN:1535-1645
  • 文摘
    Sleep disturbances are extremely prevalent in children with neurodevelopmental disorders compared to typically developing children. The diagnostic criteria for many neurodevelopmental disorders include sleep disturbances. Sleep disturbance in this population is often multifactorial and caused by the interplay of genetic, neurobiological and environmental overlap. These disturbances often present either as insomnia or hypersomnia. Different sleep disorders present with these complaints and based on the clinical history and findings from diagnostic tests, an appropriate diagnosis can be made. This review aims to provide an overview of causes, diagnosis, and treatment of sleep disturbances in neurodevelopmental disorders that present primarily with symptoms of hypersomnia and/or insomnia.

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