Bleeding outcomes associated with rivaroxaban and dabigatran in patients treated for atrial fibrillation: a systematic review and meta-analysis
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- 作者：Pravesh Kumar Bundhun ; Mohammad Zafooruddin Sani Soogund…
- 关键词：Atrial fibrillation ; Rivaroxaban ; Dabigatran ; Bleeding events ; Intracranial bleeding ; Gastrointestinal bleeding ; Oral anticoagulants
- 刊名：BMC Cardiovascular Disorders
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：1099KB
- 刊物主题：Cardiology; Cardiac Surgery; Angiology; Blood Transfusion Medicine; Internal Medicine; Medicine/Public Health, general;
- 出版者：BioMed Central
- ISSN：1471-2261
- 卷排序：17
文摘
BackgroundWarfarin is commonly used as a secondary prevention of stroke in patients with atrial fibrillation (AF). However, limitations have been observed even with the use of this medication. Recently, several newer direct oral anticoagulants (DOACs) have been approved for use by the food and drug administrations. Unfortunately, these newer drugs have seldom been compared directly with each other. Therefore, this study aimed to compare the bleeding events associated with rivaroxaban and dabigatran in patients treated for non-valvular AF.