Point-of-care testing for emergency assessment of coagulation in patients treated with direct oral anticoagulants
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- 作者：Matthias Ebner ; Ingvild Birschmann ; Andreas Peter ; Charlotte Spencer…
- 关键词：Point ; of ; care testing ; POCT ; Direct oral anticoagulants ; DOAC ; Non ; vitamin K antagonist oral anticoagulants ; NOAC ; Emergency surgery ; Anticoagulation reversal ; Thrombolysis ; Stroke
- 刊名：Critical Care
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：21
- 期：1
- 全文大小：1056KB
- 刊物主题：Intensive / Critical Care Medicine; Emergency Medicine;
- 出版者：BioMed Central
- ISSN：1364-8535
- 卷排序：21
文摘
BackgroundPoint-of-care testing (POCT) of coagulation has been proven to be of great value in accelerating emergency treatment. Specific POCT for direct oral anticoagulants (DOAC) is not available, but the effects of DOAC on established POCT have been described. We aimed to determine the diagnostic accuracy of Hemochron® Signature coagulation POCT to qualitatively rule out relevant concentrations of apixaban, rivaroxaban, and dabigatran in real-life patients.