A hemodialysis cohort study of protocol-based anticoagulation management

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• 作者：S. Lamontagne ; Tinzar Basein ; Binyue Chang ; Lakshmi Mallela
• 关键词：Hemodialysis ; Warfarin ; Anticoagulation
• 刊名：BMC Research Notes
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：10
• 期：1
• 全文大小：832KB
• 刊物主题：Biomedicine, general; Medicine/Public Health, general; Life Sciences, general;
• 出版者：BioMed Central
• ISSN：1756-0500
• 卷排序：10

文摘

BackgroundChronic hemodialysis patients frequently require anticoagulation treatment with warfarin for a variety of co-morbidities. The optimal method for monitoring and dose adjustment of warfarin-based anticoagulation in this population, however, remains unclear. To examine this more closely, we reviewed all hemodialysis patients at a single institution on chronic warfarin therapy for a 10-month period prior to and after the institution of a standardized protocol for warfarin dose adjustment and monitoring. Anticoagulation efficacy was assessed by time within the therapeutic INR range (TTR), and resource utilization was assessed by the number of weekly INR measurements required for monitoring.