Highly conserved regions in Ebola virus RNA dependent RNA polymerase may be act as a universal novel peptide vaccine target: a computational approach
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- 作者：Arafat Rahman Oany ; Tahmina Sharmin ; Afrin Sultana Chowdhury…
- 关键词：Ebola ; Computational approach ; RNA polymerase ; Epitope ; Vaccine
- 刊名：In Silico Pharmacology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：3
- 期：1
- 全文大小：1,908 KB
- 刊物主题：Pharmacology/Toxicology; Physiological, Cellular and Medical Topics; Biomedical Engineering; Medicinal Chemistry; Computational Science and Engineering;
- 出版者：Springer Berlin Heidelberg
- ISSN：2193-9616
文摘
Purpose Ebola virus (EBOV) is such kind of virus which is responsible for 23,825 cases and 9675 deaths worldwide only in 2014 and with an average diseases fatality rate between 25 % and 90 %. Although, medical technology has tried to handle the problems, there is no Food and Drug Administration (FDA)-approved therapeutics or vaccines available for the prevention, post exposure, or treatment of Ebola virus disease (EVD).