SPECT and PET imaging of angiogenesis and arteriogenesis in pre-clinical models of myocardial ischemia and peripheral vascular disease
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- 作者：Geert Hendrikx ; Stefan Vöö ; Matthias Bauwens…
- 关键词：Radiotracer imaging ; Angiogenesis ; Arteriogenesis ; Myocardial infarction ; Peripheral vascular disease
- 刊名：European Journal of Nuclear Medicine and Molecular Imaging
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：43
- 期：13
- 页码：2433-2447
- 全文大小：798 KB
- 刊物类别：Medicine
- 刊物主题：Medicine & Public Health
Nuclear Medicine
Imaging and Radiology
Orthopedics
Cardiology
Oncology - 出版者：Springer Berlin / Heidelberg
- ISSN：1619-7089
- 卷排序：43
文摘
PurposeThe extent of neovascularization determines the clinical outcome of coronary artery disease and other occlusive cardiovascular disorders. Monitoring of neovascularization is therefore highly important. This review article will elaborately discuss preclinical studies aimed at validating new nuclear angiogenesis and arteriogenesis tracers. Additionally, we will briefly address possible obstacles that should be considered when designing an arteriogenesis radiotracer.