Histopathological features of middle cerebral artery and superficial temporal artery from patients with moyamoya disease and enlightenments on clinical treatment

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• 作者：Shou-jia Sun 孙守家 ; Jian-jian Zhang 章剑剑…
• 关键词：moyamoya disease ; middle cerebral artery ; superficial temporal artery ; vasculopathy
• 刊名：Journal of Huazhong University of Science and Technology [Medical Sciences]
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：36
• 期：6
• 页码：871-875
• 全文大小：
• 刊物主题：Medicine/Public Health, general;
• 出版者：Huazhong University of Science and Technology
• ISSN：1993-1352
• 卷排序：36

文摘

The histopathological features of the middle cerebral artery (MCA) and superficial temporal artery (STA) from moyamoya disease (MMD) and their relationships with gender, age, angiography stage were explored. The causes and the clinical significance of vasculopathy of STA were also discussed. The clinical data and specimens of MCA and STA from 30 MMD patients were collected. Twelve samples of MCA and STA from non-MMD patients served as control group. Histopathological examination was then performed by measuring the thickness of intima and media, and statistical analysis was conducted. The MCA and STA specimens from MMD group had apparently thicker intima and thinner media than those from the control group. There was no significant pathological difference between the hemorrhage group and non-hemorrhage group, and between the males and females in MMD patients. Neither the age nor the digital subtraction angiography (DSA) stage was correlated with the thickness of intima in MCA and STA. MMD is a systemic vascular disease involving both intracranial and extracranial vessels. Preoperative external carotid arteriography, especially super-selective arteriography of the STA, benefits the selection of donor vessel.