Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis
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- 作者：Klementy Shchetynsky ; Lina-Marcella Diaz-Gallo…
- 关键词：Rheumatoid arthritis ; Molecular genetics ; Immunology ; Genome ; wide ; RNA ; seq
- 刊名：Arthritis Research & Therapy
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：19
- 期：1
- 全文大小：984KB
- 刊物主题：Rheumatology; Orthopedics;
- 出版者：BioMed Central
- ISSN：1478-6362
- 卷排序：19
文摘
BackgroundHere we integrate verified signals from previous genetic association studies with gene expression and pathway analysis for discovery of new candidate genes and signaling networks, relevant for rheumatoid arthritis (RA).