Recurrent pituitary ependymoma: a complex clinical problem

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• 作者：Rosie Belcher ; Harvinder S. Chahal ; Jane Evanson ; Farhad Afshar ; Silvia Marino and Ashley B. Grossman
• 关键词：Ependymoma ; Pituitary tumor ; Radiotherapy
• 刊名：Pituitary
• 出版年：2010
• 出版时间：June, 2010
• 年：2010
• 卷：13
• 期：2
• 页码：176-182
• 全文大小：993.0 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Diabetes
  Neurosurgery
  
• 出版者：Springer Netherlands
• ISSN：1573-7403

文摘

Ependymomas rarely arise from the region of the pituitary fossa, with only four cases previously reported in the literature. We present a complex case of a recurrent ependymoma of the parasellar region which has been difficult to clinically manage due to its tendency to recurrence. Our patient has had four operations over the last 28 years, with external beam radiotherapy, but still has residual tumor and is currently panhypopituitary and with significant visual loss. We believe there is considerable uncertainty as to the optimal management of any future progression, which seems likely, and are currently considering the use of radiosurgery with careful sparing of the optic chiasm, or possibly the chemotherapeutic agent temozolomide. Our case emphasises the recurrent nature of this rare but difficult tumor.