RHOA mutation in diffuse-type gastric cancer: a comparative clinicopathology analysis of 87 cases

详细信息    查看全文

• 作者：Tetsuo Ushiku ; Shumpei Ishikawa ; Miwako Kakiuchi ; Atsushi Tanaka…
• 关键词：RHOA ; Mutation ; Gastric cancer ; Diffuse type
• 刊名：Gastric Cancer
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：19
• 期：2
• 页码：403-411
• 全文大小：1,820 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  Gastroenterology
  Surgical Oncology
  Pathology
  Radiotherapy
  
• 出版者：Springer Japan
• ISSN：1436-3305

文摘

Background Recent studies have discovered recurrent RHOA mutations in diffuse-type gastric cancers. These reports show mutant RhoA is an important cancer driver and is a potential therapeutic target. This study aims to investigate the clinicopathological features of diffuse-type gastric cancers with RHOA mutation.