AURKA Phe31Ile polymorphism interacted with use of alcohol, betel quid, and cigarettes at multiplicative risk of oral cancer occurrence

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• 作者：Chi-Pin Lee ; Shang-Lun Chiang ; Chien-Hung Lee ; Yi-Shan Tsai…
• 关键词：Oral cancer ; AURKA ; CHAF1A ; CHAF1B ; TagSNPs ; Cancer susceptibility ; Environment鈥揼ene interaction
• 刊名：Clinical Oral Investigations
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：19
• 期：8
• 页码：1825-1832
• 全文大小：249 KB
• 参考文献：1.Gupta PC, Warnakulasuriya S (2002) Global epidemiology of areca nut usage. Addict Biol 7:77鈥?3CrossRef PubMed
  2.International Agency for Research on Cancer (IARC) (2004) Monographs on the evaluation of carcinogenic risks to humans volume 85. Betel-quid and areca-nut chewing and some areca-nut derived nitrosamines. Lyon: IARC
  3.Ko YC, Huang YL, Lee CH, Chen MJ, Lin LM, Tsai CC (1995) Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan. J Oral Pathol Med 24:450鈥?53CrossRef PubMed
  4.Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Bouvard V et al (2007) Carcinogenicity of alcoholic beverages. Lancet Oncol 8:292鈥?93CrossRef PubMed
  5.Chyou PH, Nomura AM, Stemmermann GN (1995) Diet, alcohol, smoking and cancer of the upper aerodigestive tract: a prospective study among Hawaii Japanese men. Int J Cancer 60:616鈥?21CrossRef PubMed
  6.Lee CH, Lee KW, Fang FM, Wu DC, Tsai SM, Chen PH et al (2012) The neoplastic impact of tobacco-free betel-quid on the histological type and the anatomical site of aerodigestive tract cancers. Int J Cancer 131:E733鈥揈743CrossRef PubMed
  7.Lee CH, Lee KW, Fang FM, Wu DC, Shieh TY, Huang HL et al (2011) The use of tobacco-free betel-quid in conjunction with alcohol/tobacco impacts early-onset age and carcinoma distribution for upper aerodigestive tract cancer. J Oral Pathol Med 40:684鈥?92CrossRef PubMed
  8.Maser RS, DePinho RA (2002) Connecting chromosomes, crisis, and cancer. Science 297:565鈥?69CrossRef PubMed
  9.Storchova Z, Pellman D (2004) From polyploidy to aneuploidy, genome instability and cancer. Nature Rev Mol Cell Biol 5:45鈥?4CrossRef
  10.International Agency for Research on Cancer (IARC) (1988) Monographs on the evaluation of carcinogenic risks to humans volume 44. Alcohol Drinking. Lyon: IARC
  11.Chiang SL, Jiang SS, Wang YJ, Chiang HC, Chen PH, Tu HP et al (2007) Characterization of arecoline-induced effects on cytotoxicity in normal human gingival fibroblasts by global gene expression profiling. Toxicol Sci 100:66鈥?4CrossRef PubMed
  12.Kaufman PD, Kobayashi R, Kessler N, Stillman B (1995) The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. Cell 81:1105鈥?114CrossRef PubMed
  13.Verreault A, Kaufman PD, Kobayashi R, Stillman B (1996) Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Cell 87:95鈥?04CrossRef PubMed
  14.Benhamou S, Tuimala J, Bouchardy C, Dayer P, Sarasin A, Hirvonen A (2004) DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract. Int J Cancer 112:901鈥?04CrossRef PubMed
  15.Elahi A, Zheng Z, Park J, Eyring K, McCaffrey T, Lazarus P (2010) The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis 23:1229鈥?234CrossRef
  16.Wang YC, Tsai YS, Huang JL, Lee KW, Kuo CC, Wang CS (2010) Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: implication for carcinogenesis. Oral Oncol 46:255鈥?62CrossRef PubMed
  17.Bischoff JR, Plowman GD (1999) The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis. Trends Cell Biol 9:454鈥?59CrossRef PubMed
  18.Giet R, Petretti C, Prigent C (2005) Aurora kinases, aneuploidy and cancer, a coincidence or a real link? Trends Cell Biol 15:241鈥?50CrossRef PubMed
  19.Wang X, Zhou YX, Qiao W, Tominaga Y, Ouchi M, Ouchi T et al (2006) Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation. Oncogene 25:7148鈥?158CrossRef PubMed
  20.Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A et al (1998) Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 20:189鈥?93CrossRef PubMed
  21.Kao SY, Chen YP, Tu HF, Liu CJ, Yu AH, Wu CH et al (2010) Nuclear STK15 expression is associated with aggressive behaviour of oral carcinoma cells in vivo and in vitro. J Pathol 222:99鈥?09PubMed
  22.Reiter R, Gais P, Jutting U, Steuer-Vogt MK, Pickhard A, Bink K et al (2006) Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma. Clin Cancer Res 12:5136鈥?141CrossRef PubMed
  23.Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan J, Chan F et al (2003) Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat Genet 34:403鈥?12CrossRef PubMed
  24.Miao X, Sun T, Wang Y, Zhang X, Tan W, Lin D (2004) Functional STK15 Phe31Ile polymorphism is associated with the occurrence and advanced disease status of esophageal squamous cell carcinoma. Cancer Res 64:2680鈥?683CrossRef PubMed
  25.Cox DG, Hankinson SE, Hunter DJ (2006) Polymorphisms of the AURKA (STK15/Aurora kinase) gene and breast cancer risk (United States). Cancer Causes Control 17:81鈥?3CrossRef PubMed
  26.Sun T, Miao X, Wang J, Tan W, Zhou Y, Yu C et al (2004) Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma. Carcinogenesis 25:2225鈥?230CrossRef PubMed
  27.Dicioccio RA, Song H, Waterfall C, Kimura MT, Nagase H, McGuire V et al (2004) STK15 polymorphisms and association with risk of invasive ovarian cancer. Cancer Epidemiol Biomarkers Prev 13:1589鈥?594PubMed
  28.Hienonen T, Salovaara R, Mecklin JP, Jarvinen H, Karhu A, Aaltonen LA (2006) Preferential amplification of AURKA 91A (Ile31) in familial colorectal cancers. Int J Cancer 118:505鈥?08CrossRef PubMed
  29.Lo YL, Yu JC, Chen ST, Yang HC, Fann CS, Mau YC et al (2005) Breast cancer risk associated with genotypic polymorphism of the mitosis-regulating gene Aurora-A/STK15/BTAK. Int J Cancer 115:276鈥?83CrossRef PubMed
  30.Feik E, Baierl A, Madersbacher S, Schatzl G, Maj-Hes A, Berges R et al (2009) Common genetic polymorphisms of AURKA and prostate cancer risk. Cancer Causes Control 20:147鈥?52CrossRef PubMed
  31.Chiang SL, Lee CP, Chang JG, Lee CH, Yeh KT, Tsai YS et al (2013) Joint effects of differentiation factor 15 and substance use of alcohol, betel quid and cigarette on risk of head and neck cancer. Head Neck Oncol 5:23
  32.Shields PG, Harris CC (1991) Molecular epidemiology and the genetics of environmental cancer. JAMA 266:681鈥?87CrossRef PubMed
  33.Chen PH, Lee KW, Chen CH, Shieh TY, Ho PS, Wang SJ et al (2011) CYP26B1 is a novel candidate gene for betel quid-related oral squamous cell carcinoma. Oral Oncol 47:594鈥?00CrossRef PubMed
  34.Chiang SL, Chen PH, Lee CH, Ko AM, Lee KW, Lin YC et al (2008) Up-regulation of inflammatory signalings by areca nut extract and role of cyclooxygenase-2-1195G鈥?gt;鈥堿 polymorphism reveal risk of oral cancer. Cancer Res 68:8489鈥?498CrossRef PubMed
  35.Tsai YS, Lin CS, Chiang SL, Lee CH, Lee KW, Ko YC (2011) Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG. Toxicol Sci 123:480鈥?90CrossRef PubMed
  36.Lee CH, Ko AM, Yen CF, Chu KS, Gao YJ, Warnakulasuriya S et al (2012) Betel-quid dependence and oral potentially malignant disorders in six Asian countries. Br J Psychiatry 201:383鈥?91CrossRef PubMed
  37.Ewart-Toland A, Dai Q, Gao YT, Nagase H, Dunlop MG, Farrington SM et al (2005) Aurora-A/STK15 T鈥?鈥?1A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types. Carcinogenesis 26:1368鈥?373CrossRef PubMed
  38.Lee CH, Ko AM, Warnakulasuriya S, Yin BL, Sunarjo ZRB et al (2011) Intercountry prevalences and practices of betel-quid use in south, southeast and eastern Asia regions and associated oral preneoplastic disorders: an international collaborative study by Asian betel-quid consortium of south and east Asia. Int J Cancer 129:1741鈥?751CrossRef PubMed
  
• 作者单位：Chi-Pin Lee (1)
  Shang-Lun Chiang (2) (7)
  Chien-Hung Lee (3)
  Yi-Shan Tsai (3)
  Zhi-Hong Wang (2)
  Chun-Hung Hua (4)
  Yuan-Chien Chen (5)
  Eing-Mei Tsai (1)
  Ying-Chin Ko (2) (6) (8)
  
  1. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  2. Environment-Omics-Diseases Research Center, China Medical University Hospital, Taichung, Taiwan
  7. Department of Health Risk Management, College of Management, China Medical University, Taichung, Taiwan
  3. Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan
  4. Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan
  5. Department of Dentistry, China Medical University Hospital, Taichung, Taiwan
  6. Graduate Institute of Clinical Medical Science, College of Medicine, China Medical University, Taichung, Taiwan
  8. 2 Yude Road, Taichung, 40447, Taiwan
  
• 刊物类别：Medicine
• 刊物主题：Dentistry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1436-3771

文摘

Objectives The expression levels of two DNA repair genes (CHAF1A and CHAF1B) and a chromosome segregation gene (AURKA) were susceptible to arecoline exposure, a major alkaloid of areca nut. We hypothesize that genetic variants of these genes might also be implicated in the risk of oral cancer and could be modified by substance use of betel quid or alcohol and cigarettes.