Innovative Verfahren der Vorhofflimmertherapie

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• 作者：Dr. A. Metzner ; E. Wissner ; T. Fink ; F. Ouyang ; K.-H. Kuck
• 关键词：Atrial fibrillation ; Pulmonary vein isolation ; Mapping ; Cryoenergy ; Laser
• 刊名：Der Kardiologe
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：10
• 期：1
• 页码：30-37
• 全文大小：748 KB
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• 作者单位：Dr. A. Metzner (1)
  E. Wissner (1)
  T. Fink (1)
  F. Ouyang (1)
  K.-H. Kuck (1)
  
  1. Abteilung für Kardiologie, Asklepios Klinik St. Georg, Lohmühlenstr. 5, 20099, Hamburg, Deutschland
  
• 刊物主题：Internal Medicine; Cardiology; Pneumology/Respiratory System; Intensive / Critical Care Medicine; Emergency Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1864-9726

文摘

Pulmonary vein isolation (PVI) is the established cornerstone in most catheter-based ablation treatment strategies for atrial fibrillation (AF); however, it is still a challenge to create contiguous, transmural and permanent ablation lesions using radiofrequency current in combination with three-dimensional mapping systems. To overcome these limitations, innovative spiral mapping and ablation catheters as well as balloon-based ablation catheters incorporating alternative energy sources, such as cryoenergy and laser were developed and evaluated and have proved their potential for safe and clinically effective PVI. In addition, novel ablation strategies, such as identification and ablation of AF-inducing foci and/or AF-perpetuating rotors using either endocardial or epicardial mapping systems were introduced and are currently under clinical evaluation. The identification and modulation of atrial ganglionic plexi (GP) and, therefore, of the autonomous nervous system is another additive ablation approach which requires further clinical evaluation.