What Risks are Associated with Primary THA in Recipients of Hematopoietic Stem Cell Transplantation?

详细信息    查看全文

• 作者：Brian P. Chalmers MD ; Cameron K. Ledford MD…
• 刊名：Clinical Orthopaedics and Related Research®
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：475
• 期：2
• 页码：475-480
• 全文大小：
• 刊物主题：Orthopedics; Surgical Orthopedics; Medicine/Public Health, general; Surgery; Sports Medicine; Conservative Orthopedics;
• 出版者：Springer US
• ISSN：1528-1132
• 卷排序：475

文摘

IntroductionAs patients who receive hematopoietic stem cell transplantation are at increased risk of avascular necrosis (AVN) and subsequent degenerative arthritis, THA may be considered in some of these patients, particularly as overall patient survival improves for patients undergoing stem-cell transplants. Patients receiving hematopoietic stem cell transplantation theoretically are at increased risk of experiencing complications, infection, and poorer implant survivorship owing to the high prevalence of comorbid conditions, immunosuppressive therapy regimens including corticosteroids, and often low circulating hematopoietic cell lines; however, there is a paucity of studies elucidating these risks.