Pd[tBuNH(S)NHP(O)(OiPr)₂-S]₂Cl₂ Complex as Air- and Moisture-Stable Catalyst for Palladium Catalyzed Suzuki Cross-Coupling Reaction

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• 作者：Damir A. Safin and Maria G. Babashkina
• 关键词：Cross ; coupling ; Phenylboronic acid ; Phenyl halide ; Suzuki– ; Miyaura reaction ; N ; phosphorylthiourea ; Palladium
• 刊名：Catalysis Letters
• 出版年：2009
• 出版时间：July, 2009
• 年：2009
• 卷：130
• 期：3-4
• 页码：679-682
• 全文大小：266.7 KB

文摘

A highly efficient Suzuki cross-coupling reaction between phenyl bromide and phenylboronic acid catalyzed by the palladium complex Pd[tBuNH(S)NHP(O)(OiPr)₂-S]₂Cl₂ in acetonitrile, toluene, THF or DMF has been investigated. The bases we have employed for this reaction were Na₂CO₃, K₂CO₃ or Cs₂CO₃. It was established that using DMF and K₂CO₃ at 100 ¡ãC shows excellent yields of the product at the catalyst amount of 0.1 mmol. The cross-coupling reactions of iodo- and chloro-benzene with phenylboronic acid were also investigated. The influence of the halide nature was as expected.