Bacterial coinfections in dengue virus disease: what we know and what is still obscure about an emerging concern

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• 作者：Mattia Trunfio ; Alessia Savoldi ; Ottavia Viganò ; Antonella d’Arminio Monforte
• 关键词：Dengue ; Bacteremia ; Coinfection ; Bacteria ; Innate immunity ; Pathogenesis
• 刊名：Infection
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：45
• 期：1
• 页码：1-10
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Infectious Diseases; General Practice / Family Medicine; Internal Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1439-0973
• 卷排序：45

文摘

PurposeDengue virus is the most frequent arthropod-borne viral infection worldwide. Simultaneously to the growth of its incidence, cases of bacterial coinfection in dengue have been increasingly reported. The clinical course of dual infections may worsen for reciprocal interactions and delays in the diagnosis, so that clinicians should be aware of this eventuality. Therefore, we reviewed literature to provide an overview of the epidemiological, clinical, and physiopathological issues related to bacterial coinfections and bacteremia in dengue.