Integration of Clinical Data Collected at Different Times for Virtual Surgery in Single Ventricle Patients: A Case Study

详细信息    查看全文

• 作者：Chiara Corsini ; Catriona Baker ; Alessia Baretta…
• 关键词：Multi ; domain model ; Cardiovascular ; Blood flow ; Congenital heart disease ; Lumped parameter model ; Finite volume method
• 刊名：Annals of Biomedical Engineering
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：43
• 期：6
• 页码：1310-1320
• 全文大小：1,959 KB
• 参考文献：1.Baretta, A., C. Corsini, A. L. Marsden, I. E. Vignon-Clementel, T.-Y. Hsia, G. Dubini, F. Migliavacca, and G. Pennati, The Modeling of Congenital Hearts Alliance (MOCHA). Respiratory effects on hemodynamics in patient-specific CFD models of the Fontan circulation under exercise conditions. Eur. J. Mech. B-Fluid. 35:61-9, 2012.
  2.Baretta, A., C. Corsini, W. Yang, I. E. Vignon-Clementel, A. L. Marsden, J. A. Feinstein, T.-Y. Hsia, G. Dubini, F. Migliavacca, G. Pennati, and The Modeling of Congenital Hearts Alliance (MOCHA) Investigators. Virtual surgeries in patients with congenital heart disease: a multi-scale modelling test case. Philos. Trans. R. Soc. A 369:4316-330, 2011.
  3.Coppoletta, J. M., and S. B. Wolbach. Body length and organ weights of infants and children. A study of the body length and normal weights of the more important vital organs of the body between birth and twelve years of age. Am. J. Pathol. 9:55-0, 1933.PubMed Central PubMed
  4.Corsini, C., C. Baker, E. Kung, S. Schievano, G. Arbia, A. Baretta, G. Biglino, F. Migliavacca, G. Dubini, G. Pennati, A. Marsden, I. Vignon-Clementel, A. Taylor, T. Y. Hsia, and A. Dorfman for the Modeling of Congenital Hearts Alliance Mocha Investigators. An integrated approach to patient-specific predictive modeling for single ventricle heart palliation. Comput. Methods Biomech. Biomed. Eng. 17:1572-589, 2014.
  5.de Zélicourt, D. A., C. M. Haggerty, K. S. Sundareswaran, B. S. Whited, J. R. Rossignac, K. R. Kanter, J. W. Gaynor, T. L. Spray, F. Sotiropoulos, M. A. Fogel, and A. P. Yoganathan. Individualized computer-based surgical planning to address pulmonary arteriovenous malformations in patients with a single ventricle with an interrupted inferior vena cava and azygous continuation. J. Thorac. Cardiovasc. Surg. 141:1170-177, 2011.PubMed Central PubMed View Article
  6.Fontan, F., and E. Baudet. Surgical repair of tricuspid atresia. Thorax 26:240-48, 1971.PubMed Central PubMed View Article
  7.Giannessi, M., M. Ursino, and W. B. Murray. The design of a digital cerebrovascular simulation model for teaching and research. Anesth. Analg. 107:1997-008, 2008.PubMed View Article
  8.Haggerty, C. M., D. A. de Zelicourt, K. Sundareswaran, K. Pekkan, B. Whited, J. Rossignac, M. A. Fogel, and A. P. Yoganathan. Hemodynamic assessment of virtual surgery options for a failing Fontan using lumped parameter simulation. Comput. Cardiol. 36:389-92, 2009.
  9.Hill, K. D., D. Janssen, D. P. Ohmstede, and T. P. Doyle. Pulmonary venous wedge pressure provides a safe and accurate estimate of pulmonary arterial pressure in children with shunt-dependent pulmonary blood flow. Catheter. Cardiovasc. Interv. 74:747-52, 2009.PubMed View Article
  10.Kim, H. J., K. E. Jansen, and C. A. Taylor. Incorporating autoregulatory mechanisms of the cardiovascular system in three-dimensional finite element models of arterial blood flow. Ann. Biomed. Eng. 38:2314-330, 2010.PubMed View Article
  11.Kung, E., A. Baretta, C. Baker, G. Arbia, G. Biglino, C. Corsini, S. Schievano, I. E. Vignon-Clementel, G. Dubini, G. Pennati, A. Taylor, A. Dorfman, A. M. Hlavacek, A. L. Marsden, T. Y. Hsia, F. Migliavacca, and the Modeling of Congenital Hearts Alliance (MOCHA) Investigators. Predictive modeling of the virtual Hemi-Fontan operation for second stage single ventricle palliation: two patient-specific cases. J. Biomech. 46:423-29, 2013.
  12.Li, J., A. Bush, I. Schulze-Neick, D. J. Penny, A. N. Redington, and L. S. Shekerdemian. Measured versus estimated oxygen consumption in ventilated patients with congenital heart disease: the validity of predictive equations. Crit. Care Med. 31:1235-240, 2003.PubMed View Article
  13.Li, M., D. E. Scott, R. Shandas, K. R. Stenmark, and W. Tan. High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells. Ann. Biomed. Eng. 37:1082-092, 2009.PubMed Central PubMed View Article
  14.Magee, A. G., B. W. McCrindle, J. Mawson, L. N. Benson, W. G. Williams, and R. M. Freedom. Systemic venous collateral development after the bidirectional cavopulmonary anastomosis. Prevalence and predictors. J. Am. Coll. Cardiol. 32:502-08, 1998.PubMed View Article
  15.Marsden, A. L. Simulation based planning of surgical interventions in pediatric cardiology. Phys. Fluids 25:101303, 2013.
  16.McElhinney, D. B., V. M. Reddy, F. L. Hanley, and P. Moore. Systemic venous collateral channels causing desaturation after bidirectional cavopulmonary anastomosis: evaluation and management. J. Am. Coll. Cardiol. 30:817-24, 1997.PubMed View Article
  17.Migliavacca, F., R. Balossino, G. Pennati, G. Dubini, T. Y. Hsia, M. R. de Leval, and E. L. Bove. Multiscale modelling in biofluidynamics: application to reconstructive paediatric cardiac surgery. J. Biomech. 39:1010-020, 2006.PubMed View Article
  18.Pennati, G., C. Corsini, D. Cosentino, T. Y. Hsia, V. S. Luisi, G. Dubini, and F. Migliavacca. B
• 作者单位：Chiara Corsini (1)
  Catriona Baker (2)
  Alessia Baretta (1)
  Giovanni Biglino (2)
  Anthony M. Hlavacek (3)
  Tain-Yen Hsia (2)
  Ethan Kung (4) (5)
  Alison Marsden (5)
  Francesco Migliavacca (1)
  Irene Vignon-Clementel (6) (7)
  Giancarlo Pennati (1)
  The Modeling of Congenital Hearts Alliance (MOCHA) Investigators
  
  1. Laboratory of Biological Structure Mechanics, Department of Chemistry, Materials and Chemical Engineering ‘Giulio Natta- Politecnico di Milano, Milan, Italy
  2. Centre for Cardiovascular Imaging, UCL Institute of Cardiovascular Science, and Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK
  3. Division of Pediatric Cardiology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA
  4. Mechanical Engineering Department, Clemson University, Clemson, SC, USA
  5. Mechanical and Aerospace Engineering Department, University of California San Diego, San Diego, CA, USA
  6. INRIA Paris-Rocquencourt, Le Chesnay Cedex, France
  7. Laboratoire Jacques-Louis Lions, UPMC Université Paris 6, Paris, France
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Biomedicine
  Biomedical Engineering
  Biophysics and Biomedical Physics
  Mechanics
  Biochemistry
  
• 出版者：Springer Netherlands
• ISSN：1573-9686

文摘

Newborns with single ventricle physiology are usually palliated with a multi-staged procedure. When cardiovascular complications e.g., collateral vessel formation occur during the inter-stage periods, further treatments are required. An 8-month-old patient, who underwent second stage (i.e., bi-directional Glenn, BDG) surgery at 4?months, was diagnosed with a major veno-venous collateral vessel (VVC) which was endovascularly occluded to improve blood oxygen saturations. Few clinical data were collected at 8?months, whereas at 4?months a more detailed data set was available. The aim of this study is threefold: (i) to show how to build a patient-specific model describing the hemodynamics in the presence of VVC, using patient-specific clinical data collected at different times; (ii) to use this model to perform virtual VVC occlusion for quantitative hemodynamics prediction; and (iii) to compare predicted hemodynamics with post-operative measurements. The three-dimensional BDG geometry, resulting from the virtual surgery on the first stage model, was coupled with a lumped parameter model (LPM) of the 8-month patient’s circulation. The latter was developed by scaling the 4-month LPM to account for changes in vascular impedances due to growth and adaptation. After virtual VVC closure, the model confirmed the 2?mmHg BDG pressure increase, as clinically observed, suggesting the importance of modeling vascular adaptation following the BDG procedure.