No Difference in Early Analgesia Between Liposomal Bupivacaine Injection and Intrathecal Morphine After TKA

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• 作者：John W. Barrington MD ; Roger H. Emerson MD…
• 刊名：Clinical Orthopaedics and Related Research®
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：475
• 期：1
• 页码：94-105
• 全文大小：
• 刊物主题：Orthopedics; Surgical Orthopedics; Medicine/Public Health, general; Surgery; Sports Medicine; Conservative Orthopedics;
• 出版者：Springer US
• ISSN：1528-1132
• 卷排序：475

文摘

BackgroundOpioid analgesics have been a standard modality for postoperative pain management after total knee arthroplasty (TKA) but are also associated with increased risk of nausea, pruritus, vomiting, respiratory depression, prolonged ileus, and cognitive dysfunction. There is still a need for a method of anesthesia that can deliver effective long-term postoperative pain relief without incurring the high cost and health burden of opioids and nerve blocks.