Quorum quenching–Stören friede zwischenbakterieller Beziehungen

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• 作者：Nancy Weiland-Bräuer ; Ruth A. Schmitz-Streit
• 刊名：BIOspektrum
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：22
• 期：4
• 页码：362-364
• 全文大小：588 KB
• 刊物主题：Life Sciences, general; Biochemistry, general; Human Genetics; Microbiology; Developmental Biology; Pharmacology/Toxicology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1868-6249
• 卷排序：22

文摘

Most bacteria are able to grow in biofilms in which they effectively resist antimicrobial agents. This leads to a general problem, since traditional treatments of bacteria and prevention strategies become mostly ineffective. Novel strategies for biofilm inhibition are thus urgently required. Compounds interfering with cell-cell communication (quorum sensing) crucial for biofilm formation are promising targets for alternative strategies. Here, we report on a recently established assay enabling identification of quorum quenching compounds from environmental samples.