One-pot synthesis of N-aryl 1,4-dihydropyridine derivatives and their biological activities

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• 作者：ISAIVANI DHINAKARAN ; VEDIAPPEN PADMINI ; NATTAMAI BHUVANESH
• 关键词：One ; pot synthesis ; enamine ; radical scavenging ; cytotoxicity ; dihydropyridine
• 刊名：Journal of Chemical Sciences
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：127
• 期：12
• 页码：2201-2209
• 全文大小：1,469 KB
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• 作者单位：ISAIVANI DHINAKARAN (1)
  VEDIAPPEN PADMINI (1)
  NATTAMAI BHUVANESH (2)
  
  1. Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, 625 021, Tamil Nadu, India
  2. Department of Chemistry, Texas A&M University, College Station, TX, 77842, USA
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Chemistry
  
• 出版者：Springer India
• ISSN：0973-7103

文摘

Highly efficient, one pot synthesis of N-aryl, 1,4-dihydopyridines was carried out by four component reaction. Synthesized 1,4-dihydropyridines were screened for their cytotoxicity against A549 cell line. All the synthesized compounds exhibited better DPPH radical scavenging activity.