Diagnosis and treatment of cystic renal cell carcinoma

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• 作者：Jiexiu Zhang (1)
  Bianjiang Liu (1)
  Ninghong Song (1)
  Lixin Hua (1)
  Zengjun Wang (1)
  Min Gu (1)
  Changjun Yin (1)
  
• 关键词：Cystic renal cell carcinoma ; Diagnosis ; Nephrectomy ; Nephron ; sparing surgery
• 刊名：World Journal of Surgical Oncology
• 出版年：2013
• 出版时间：December 2013
• 年：2013
• 卷：11
• 期：1
• 全文大小：224KB
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• 作者单位：Jiexiu Zhang (1)
  Bianjiang Liu (1)
  Ninghong Song (1)
  Lixin Hua (1)
  Zengjun Wang (1)
  Min Gu (1)
  Changjun Yin (1)
  
  1. Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China
  

文摘

Background To summarize the diagnosis and treatment of cystic renal cell carcinoma (CRCC). Methods A retrospective study was conducted on 13 patients with CRCC at our center from August 2004 to April 2012. The pathologic features, clinical manifestation, imaging characteristics, treatment, and prognosis of CRCC were summarized according to available literature. Results Of the 13 patients, 11 were diagnosed with CRCC by preoperative B ultrasonography and computed tomography (CT) scan. The remaining two cases were initially misdiagnosed with simple renal cysts. Open radical nephrectomy was performed on two of the 13 cases, laparoscopic radical nephrectomy on seven cases, and open partial nephrectomy on four cases. All diagnoses of CRCC were confirmed by pathological examination. After the operation, all patients had an uneventful recovery. During the follow-up (range, 6-0 months), the serum creatinine concentrations and GFR of the partially removed kidneys remained stable within the normal range. No tumor recurrence or metastasis occurred. Conclusions By combining imaging examinations (B ultrasonography and CT scan) with intraoperative pathological examination, most cases of CRCC can be diagnosed and treated promptly and accurately. Nephrectomy is the first-line therapy. Nephron-sparing surgery should be preferred for CRCC. After a successful operation, the prognosis of CRCC is good.