Comparison of deep anterior lamellar keratoplasty and penetrating keratoplasty with respect to postoperative corneal sensitivity and tear film function
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- 作者：Xiaolei Lin (1)
Binbin Xu (1)
Yifang Sun (1)
Jing Zhong (1)
Weilan Huang (1)
Jin Yuan (1) - 关键词：Deep anterior lamellar keratoplasty ; Penetrating keratoplasty ; Dry eye ; Tear film function ; Corneal sensitivity
- 刊名：Graefe's Archive for Clinical and Experimental Ophthalmology
- 出版年：2014
- 出版时间：November 2014
- 年：2014
- 卷：252
- 期：11
- 页码：1779-1787
- 全文大小：684 KB
- 参考文献：1. The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 5: 93-07
2. McCarty CA, Bansal AK, Livingston PM, Stanislavsky YL, Taylor HR (1998) The epidemiology of dry eye in Melbourne, Australia. Ophthalmology 105:1114-119 CrossRef
3. Lin PY, Tsai SY, Cheng CY, Liu JH, Chou P, Hsu WM (2003) Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study. Ophthalmology 110:1096-101 CrossRef
4. Hirayama Y, Satake Y, Hirayama M, Shimazaki-Den S, Konomi K, Shimazaki J (2013) Changes in corneal sensation, epithelial damage, and tear function after descemet stripping automated endothelial keratoplasty. Cornea 32:1255-259 CrossRef
5. Management and therapy of dry eye disease: report of the Management and Therapy Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 5:163-78
6. Muller LJ, Marfurt CF, Kruse F, Tervo TM (2003) Corneal nerves: structure, contents and function. Exp Eye Res 76:521-42 CrossRef
7. Fu Y, Liu J, Tseng SC (2012) Ocular surface deficits contributing to persistent epithelial defect after penetrating keratoplasty. Cornea 31:723-29 CrossRef
8. Darwish T, Brahma A, Efron N, O’Donnell C (2007) Subbasal nerve regeneration after penetrating keratoplasty. Cornea 26:935-40 CrossRef
9. Hara S, Kojima T, Dogru M, Uchino Y, Goto E, Matsumoto Y, Kawakita T, Tsubota K, Shimazaki J (2013) The impact of tear functions on visual outcome following keratoplasty in eyes with keratoconus. Graefes Arch Clin Exp Ophthalmol 251:1763-770 CrossRef
10. Oh BL, Kim MK, Wee WR (2013) Comparison of clinical outcomes of same-size grafting between deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus. Korean J Ophthalmol 27:322-30 CrossRef
11. Ceccuzzi R, Zanardi A, Fiorentino A, Tinelli C, Bianchi PE (2010) Corneal sensitivity in keratoconus after penetrating and deep anterior lamellar keratoplasty. Ophthalmologica 224:247-50 CrossRef
12. Al-Aqaba MA, Otri AM, Fares U, Miri A, Dua HS (2012) Organization of the regenerated nerves in human corneal grafts. Am J Ophthalmol 153:29-7 CrossRef
13. Anwar M, Teichmann KD (2002) Big-bubble technique to bare Descemet’s membrane in anterior lamellar keratoplasty. J Cataract Refract Surg 28:398-03 CrossRef
14. De Paiva CS, Pflugfelder SC (2004) Corneal epitheliopathy of dry eye induces hyperesthesia to mechanical air jet stimulation. Am J Ophthalmol 137:109-15 CrossRef
15. Sakata LM, Wong TT, Wong HT, Kumar RS, Htoon HM, Aung HT, He M, Aung T (2010) Comparison of Visante and slit-lamp anterior segment optical coherence tomography in imaging the anterior chamber angle. Eye (Lond) 24:578-87 CrossRef
16. Leung CK, Cheung CY, Li H, Dorairaj S, Yiu CK, Wong AL, Liebmann J, Ritch R, Weinreb R, Lam DS (2007) Dynamic analysis of dark–light changes of the anterior chamber angle with anterior segment OCT. Invest Ophthalmol Vis Sci 48:4116-122 CrossRef
17. Koh S, Maeda N, Nakagawa T, Nishida K (2012) Quality of vision in eyes after selective lamellar keratoplasty. Cornea 31(Suppl 1):S45–S49 Binbin Xu (1)
Yifang Sun (1)
Jing Zhong (1)
Weilan Huang (1)
Jin Yuan (1)
1. Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, China - ISSN：1435-702X
文摘
Purpose To investigate tear film function, central and peripheral corneal sensitivity and corneal subbasal nerve morphology in the cornea after deep anterior lamellar keratoplasty (DALK) compared with penetrating keratoplasty (PK). Methods This prospective study compared the changes in 16 eyes of 16 patients who underwent DALK (DALK group) with those in 28 eyes of 28 patients who underwent PK (PK group). Thirty healthy volunteers were also included as controls. Tear functions were evaluated using tear break-up time (TBUT), tear meniscus height (TMH) and corneal fluorescein staining. Corneal sensation was measured with a Cochet-Bonnet esthesiometer. Corneal subbasal nerve morphology was evaluated using in vivo confocal microscopy (IVCM). The patients were examined 1, 3, 6, 9 and 12?months after keratoplasty. Results Postoperatively, TMH recovered significantly faster in the DALK group than in the PK group (p--.05), and the postoperative TBUT was much higher in the DALK group compared with the PK group (p--.05). Central and peripheral corneal sensitivity remained lower in both the PK and DALK groups at 12?months after surgery compared with the control group (p--.05). The peripheral corneal sensitivity of the host cornea was significantly higher than the central corneal sensitivity (p--.05). No significant difference was found in corneal sensitivity between the PK and DALK groups. There was no significant correlation between corneal sensitivity and tear film function after PK or DALK. Conclusions Tear film function was restored more rapidly after DALK compared with PK, but there was no significant difference in corneal sensitivity between PK and DALK.