Postmortem angiography using femoral cannulation and postmortem microbiology

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• 作者：Cristian Palmiere ; Coraline Egger…
• 关键词：Postmortem bacteriology ; Postmortem biochemistry ; Postmortem angiography ; Infection ; Blood cultures
• 刊名：International Journal of Legal Medicine
• 出版年：2015
• 出版时间：July 2015
• 年：2015
• 卷：129
• 期：4
• 页码：861-867
• 全文大小：143 KB
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• 作者单位：Cristian Palmiere (1)
  Coraline Egger (1)
  Silke Grabherr (1)
  Katia Jaton-Ogay (2)
  Gilbert Greub (2) (3)
  
  1. University Centre of Legal Medicine, University Hospital Center and University of Lausanne, Rue du Bugnon 21, 1011, Lausanne, Switzerland
  2. Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland
  3. Service of Infectious Diseases, University Hospital Center, Lausanne, Switzerland
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Forensic Medicine
  Medical Law
  Medicine/Public Health, general
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1437-1596

文摘

Despite the undeniable advantages of postmortem angiography, numerous questions have arisen concerning the influence that the injected contrast media may exercise on biological fluids and tissues collected for toxicological and biochemical investigations. Moreover, cardiac blood for microbiological investigations cannot be obtained post-angiography. In this study, we examined whether the peripheral blood collected prior to postmortem angiography, using percutaneous access to femoral vessels after skin surface disinfection, could be suitable for microbiological investigations when postmortem angiography with femoral vessel cannulation is also performed. A total of 66 cases were included in the study and were divided into two subgroups (angiography and bacteriology group, 33 cases and control group, 33 cases). Autopsies, histology, toxicology, bacteriology, and biochemical investigations (procalcitonin, C-reactive protein, interleukin-6, and soluble triggering receptors expressed on myeloid cells type 1) were performed in all cases. No statistically significant differences between the two groups were noted, and identified category distribution (death unrelated to infection, true infection, false positive, and undetermined) was rather similar in both studied populations. These preliminary results suggest that postmortem angiography using a femoral approach does not constitute an impediment to the collection of peripheral blood for microbiology and vice versa. Moreover, the use of femoral blood for microbiology does not lead to an increased risk of doubtful results.