A kind of biomolecular probe sensor based on TFBG surface plasma resonance

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• 作者：Mengwei Xue (1)
  Qi Jiang (1)
  Chengjia Zhang (2)
  Jianqiang Lin (2)
  
  1. School of Control Science and Engineering ; Shandong University ; Jinan ; 250061 ; China
  2. State Key Lab of Microbial Technology ; School of Life Science ; Shandong University ; Jinan ; 250100 ; China
  
• 关键词：TFBG ; nanostructure golden layer ; surface plasma resonance ; biosensor
• 刊名：Photonic Sensors
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：5
• 期：2
• 页码：102-108
• 全文大小：1,098 KB
• 参考文献：1. Jiang, Q, Lv, D D, Yu, M H, Kang, L M, Ouyang, J (2013) The experiment research on solution refractive index sensor based on tilted fiber Bragg grating. Spectroscopy and Spectral Analysis 33: pp. 3425-3431
  2. Huet, A C, Charlier, C, Singh, G, Godefroy, S B, Leivo, J, Vehni盲inen, M (2008) Development of an optical surface plasmon resonance biosensor assay for (fluoro) quinolones in egg, fish, and poultry meat. Analytica Chimica Acta 623: pp. 195-203 CrossRef
  3. Rebe, R S, Bremer, M G, Haasnoot, W, Norde, W (2009) Label-free and multiplex detection of antibiotic residues in milk using imaging surface plasmon resonance-based immunosensor. Analytical chemistry 81: pp. 7743-7749 CrossRef
  4. Song, Y, Liu, M, Wang, S (2013) Surface plasmon resonance sensor for phosmet of agricultural products at the ppt detection level. Journal of Agricultural and Food Chemistry 61: pp. 2625-2630 CrossRef
  5. Shevchenko, Y, Blair, D, Derosa, M C, Albert, J (2008) DNA target detection using gold-coated tilted fiber Bragg gratings in aqueous media. Conference on Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science, San Jose. pp. 1-2
  6. Shevchenko, Y, Camci-Unal, G, Cuttica, D F, Dokmeci, M R, Albert, J, Khademhosseini, A (2014) Surface plasmon resonance fiber sensor for real-time and label-free monitoring of cellular behavior. Biosensors and Bioelectronics 56: pp. 359-367 CrossRef
  
• 刊物类别：Physics and Astronomy
• 刊物主题：Chinese Library of Science
  Laser Technology and Physics and Photonics
  Microwaves, RF and Optical Engineering
  Measurement Science and Instrumentation
  Optics, Optoelectronics, Plasmonics and Optical Devices
  
• 出版者：University of Electronic Science and Technology of China, co-published with Springer
• ISSN：2190-7439

文摘

This paper reports the application of the biomolecular probe sensor based on the tilted fiber Bragg grating (TFBG) surface plasma resonance (SPR) which can recognize the specificity of the specific molecule by depositing sensitive biological membrane outside the active golden layer. The method of self-assembly was used to make the fixed sensitive biological membrane to achieve the best effect in the experiment. To illustrate the specific recognition of the DNA molecule, the TFBG-SPR biosensor was exposed to complementary DNA solutions with the concentration of 0.1 mmol/L and 0.05 mmol/L, respectively. The resonance wavelength of the TFBG-SPR biosensor increased gradually, indicating that the hybridization with the complementary DNA molecules changed the effective refractive index in the vicinity of the golden layer. Furthermore, the results illustrated the feasibility of the biomolecular probe sensor based on the TFBG surface plasma resonance for detecting the specific molecule.