Risk Factors of Postoperative Upper Gastrointestinal Bleeding Following Colorectal Resections
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  • 作者:Zhobin Moghadamyeghaneh (1)
    Steven D. Mills (1)
    Alessio Pigazzi (1)
    Joseph C. Carmichael (1)
    Michael J. Stamos (1) (2)
  • 关键词:Gastrointestinal bleeding ; Colorectal surgery ; Postoperative bleeding
  • 刊名:Journal of Gastrointestinal Surgery
  • 出版年:2014
  • 出版时间:July 2014
  • 年:2014
  • 卷:18
  • 期:7
  • 页码:1327-1333
  • 全文大小:
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  • 作者单位:Zhobin Moghadamyeghaneh (1)
    Steven D. Mills (1)
    Alessio Pigazzi (1)
    Joseph C. Carmichael (1)
    Michael J. Stamos (1) (2)

    1. Department of Surgery, School of Medicine, University of California, Irvine, Orange, CA, USA
    2. 333 City Blvd. West Suite 700, Orange, CA, 92868, USA
  • ISSN:1873-4626
文摘
There is limited data regarding the risk factors of postoperative upper GI bleeding (UGIB) in patients undergoing colorectal resection. We sought to identify risk factors of UGIB after colorectal resection. The NIS database was used to evaluate all patients who had colorectal resection complicated by UGIB between 2002 and 2010. Multivariate analysis using logistic regression was performed to quantify the association of preoperative variables with postoperative UGIB. We sampled a total of 2,514,228 patients undergoing colorectal resection, of which, 12,925 (0.5?%) suffered a postoperative UGIB. The mortality of patients who had UGIB was significantly greater than patients without UGIB (14.9 vs. 4.7?%; OR, 3.57; CI, 3.40-.75; P-lt;-.01). Patients suffering from UGIB had an associated 14.9?% inhospital mortality. History of chronic peptic ulcer disease (6.75; CI, 5.75-.91; P-lt;-.01) and emergency admission (OR, 4.27; CI, 4.09-.45; P-lt;-.01) are associated with UGIB. Duodenal ulcer as the source of bleeding is a mortality predictors of patients (OR, 1.71; CI, 1.49-.97; P-lt;-.01). Postoperative UGIB occurs in less than 1?% of colorectal resections. However, patients suffering from postoperative UGIB are over three times more likely to die. Chronic peptic ulcer disease and emergency admission are respectively the strongest predictors of postoperative UGIB.

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