Efficacy of high-intensity focused ultrasound-assisted hepatic resection (HIFU-AR) on blood loss reduction in patients with liver metastases requiring hepatectomy: study protocol for a randomized controlled trial
详细信息 查看全文
- 作者：Aurélien Dupré ; David Pérol ; Ellen Blanc ; Patrice Peyrat ; Valéria Basso ; Yao Chen…
- 关键词：High ; intensity focused ultrasound ; HIFU ; Liver surgery ; Hepatectomy ; Liver metastasis ; Liver transection ; Blood loss ; Blood transfusion ; Randomized trial
- 刊名：Trials
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：741KB
- 刊物主题：Medicine/Public Health, general; Biomedicine, general; Statistics for Life Sciences, Medicine, Health Sciences;
- 出版者：BioMed Central
- ISSN：1745-6215
- 卷排序：18
文摘
BackgroundLiver resection is the only potentially curative treatment for colorectal liver metastases (LM). It is considered a safe procedure, but is often associated with blood loss during liver transection. Blood transfusions are frequently needed, but they are associated with increased morbidity and risk of recurrence. Many surgical devices have been developed to decrease blood loss. However, none of them has proven superior to the standard crushing technique. We developed a new, powerful intra-operative high-intensity focused ultrasound (HIFU) transducer which destroys tissue by coagulative necrosis. We aim to evaluate whether HIFU-assisted liver resection (HIFU-AR) results in reduced blood loss.