Prophages and adaptation of Staphylococcus aureus ST398 to the human clinic
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- 作者：Seydina M. Diene ; Anna Rita Corvaglia ; Patrice François…
- 关键词：Staphylococcus aureus ; CC398 lineage ; Phage content ; Prophage ; Evolution ; Livestock ; associated ; φ3 ; prophage ; Bloodstream infections
- 刊名：BMC Genomics
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：1847KB
- 刊物主题：Life Sciences, general; Microarrays; Proteomics; Animal Genetics and Genomics; Microbial Genetics and Genomics; Plant Genetics & Genomics;
- 出版者：BioMed Central
- ISSN：1471-2164
- 卷排序：18
文摘
BackgroundIt has been suggested that prophages in the ST398 S. aureus clone are responsible for expanding ST398's spectrum of action and increasing its ability to cause human infections. We carried out the first characterization of the various prophages carried by 76 ST398 bloodstream infection (BSI) isolates obtained over 9 years of observation.