Differences in the clinical phenotype of adenomyosis and leiomyomas: a retrospective, questionnaire-based study

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• 作者：Bettina Boeer (1)
  Markus Wallwiener (2)
  Joachim Rom (2)
  Birgitt Schoenfisch (1)
  Sara Y. Brucker (1)
  Florin A. Taran (1)
  
• 关键词：Adenomyosis ; Leiomyomas
• 刊名：Archives of Gynecology and Obstetrics
• 出版年：2014
• 出版时间：June 2014
• 年：2014
• 卷：289
• 期：6
• 页码：1235-1239
• 全文大小：
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• 作者单位：Bettina Boeer (1)
  Markus Wallwiener (2)
  Joachim Rom (2)
  Birgitt Schoenfisch (1)
  Sara Y. Brucker (1)
  Florin A. Taran (1)
  
  1. Department of Obstetrics and Gynecology, University Women’s Clinic, Calwerstr. 7, 72076, Tuebingen, Germany
  2. Department of Obstetrics and Gynecology, University Women’s Clinic, Heidelberg, Germany
  
• ISSN：1432-0711

文摘

Purpose To compare women undergoing laparoscopic hysterectomy with adenomyosis and women with leiomyomas. Materials and methods Retrospective and questionnaire-based study was conducted at the Department of Obstetrics and Gynecology, University Women’s Clinic, Tuebingen, Germany. The study sample comprised a total of 454 women who underwent hysterectomy for adenomyosis or leiomyomas and responded to the questionnaire; 52 (11.4?%) women with a histologic diagnosis of adenomyosis and 452 (88.6?%) women with a histologic diagnosis of leiomyomas. Results Both groups of patients had enlarged uteri, but women with adenomyosis had a lower mean uterine weight as compared to women with leiomyomas (p?<?0.001). Women with adenomyosis had significantly more pregnancies (p?=?0.003), were more likely to have more than one pregnancy (p?=?0.033) or more than one delivery (p?=?0.025) as compared to women with leiomyomas. In addition, women with adenomyosis had a significantly higher surgical procedure score (p?=?0.017), had more frequently a history of laparotomy (p?=?0.042) and a history of Cesarean section as compared to women with leiomyomas only (p?=?0.024). Significantly, more women with adenomyosis had pelvic pain or pressure as compared to women with leiomyomas (p?=?0.045). We observed no differences between the two groups of patients regarding pelvic pain during the menstrual period, irregular menstrual periods, heavy bleeding, painful sexual intercourse and urination problems. Furthermore, we observed no differences in the therapeutic impact of the surgical procedure between the two patient groups. Conclusions Women with a histologic diagnosis of adenomyosis differ from women who have only leiomyomas at the time of hysterectomy.