Disputing Lamarckian epigenetic inheritance in mammals

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• 作者：Emma Whitelaw (1)
  
  1. Department of Genetics ; La Trobe University ; Bundoora ; VIC ; 3086 ; Australia
  
• 刊名：Genome Biology
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：16
• 期：1
• 全文大小：269 KB
• 参考文献：1. Iqbal K, Tran DA, Li AX, Warden C, Bai AY, Singh P, et al. Epigenome reprogramming in the mammalian germline corrects deleterious effects of endocrine disruptors globally and at imprinted genes. Genome Biol. 2015, 16:619
  2. Anway, MD, Cupp, AS, Uzumcu, M, Skinner, MK (2005) Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 308: pp. 1466-9 CrossRef
  3. Dolinoy, DC, Huang, D, Jirtle, RL (2007) Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci U S A 104: pp. 13056-61 CrossRef
  4. Daxinger, L, Whitelaw, E (2012) Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nat Rev Genet 13: pp. 153-62 CrossRef
  5. Dias, BG, Ressler, KJ (2014) Experimental evidence needed to demonstrate inter- and trans-generational effects of ancestral experiences in mammals. BioEssays 36: pp. 919-23 CrossRef
  6. Heard, E, Martienssen, RA (2014) Transgenerational epigenetic inheritance: myths and mechanisms. Cell 157: pp. 95-109 CrossRef
  7. Ng, S-F, Lin, RCY, Laybutt, DR, Barres, R, Owens, JA, Morris, MJ (2010) Chronic high-fat diet in fathers programs [bgr]-cell dysfunction in female rat offspring. Nature 467: pp. 963-6 CrossRef
  8. Carone, BR, Fauquier, L, Habib, N, Shea, JM, Hart, CE, Li, R (2010) Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell 143: pp. 1084-96 CrossRef
  9. Schulz, LC (2010) The Dutch Hunger Winter and the developmental origins of health and disease. Proc Natl Acad Sci U S A 107: pp. 16757-8 CrossRef
  10. Yehuda, R, Engel, SM, Brand, SR, Seckl, J, Marcus, SM, Berkowitz, GS (2005) Transgenerational effects of posttraumatic stress disorder in babies of mothers exposed to the world trade center attacks during pregnancy. J Clin Endocrinol Metab 90: pp. 4115-8 CrossRef
  11. Pembrey, ME, Bygren, LO, Kaati, G, Edvinsson, S, Northstone, K, Sjostrom, M (2005) Sex-specific, male-line transgenerational responses in humans. Eur J Hum Genet 14: pp. 159-66 CrossRef
  12. Stouder, C, Paoloni-Giacobino, A (2010) Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm. Reproduction 139: pp. 373-9 CrossRef
  
• 刊物主题：Animal Genetics and Genomics; Human Genetics; Plant Genetics & Genomics; Microbial Genetics and Genomics; Fungus Genetics; Bioinformatics;
• 出版者：BioMed Central
• ISSN：1465-6906

文摘

A recent study finds that changes to transcription and DNA methylation resulting from in utero exposure to environmental endocrine-disrupting chemicals are not inherited across generations.