Dependence on Over the Counter (OTC) Codeine Containing Analgesics: Treatment and Recovery with Buprenorphine Naloxone

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• 作者：Marie Claire Van Hout ; Ide Delargy…
• 关键词：Codeine ; Opioid analgesic dependence ; Opioid painkiller dependence ; Buprenorphine ; naloxone ; Suboxone®
• 刊名：International Journal of Mental Health and Addiction
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：14
• 期：5
• 页码：873-883
• 全文大小：359 KB
• 刊物主题：Public Health; Health Psychology; Psychology, general; Rehabilitation; Psychiatry; Community and Environmental Psychology;
• 出版者：Springer US
• ISSN：1557-1882
• 卷排序：14

文摘

Misuse and dependence on prescribed and over the counter (OTC) codeine-combination analgesics is an emerging public health concern. We present a clinical case series of four adult patients dependent on OTC codeine combination analgesics in Ireland. Cases (two males/two females, aged 44–57 years) were consuming between 12 and 72 codeine-containing tablets/day. In three cases, consumption was linked to pain, with on-going misuse reflecting dependence on codeine. Cases were initiated on buprenorphine-naloxone (Suboxone®), stabilised on doses of between 4 mg/1 mg and 14 mg/3.5 mg per day and remain on treatment without additional opioid use, as verified by drug screening reports. Although anecdotal, these cases show the potential of effective opioid assisted treatment (OAT) using buprenorphine-naloxone (Suboxone®) to successfully treat this distinct form of opioid dependence disorder. Optimal service provision should recognise unique patient profiles and needs for this form of opioid dependence and incorporate psycho-social supports.