“Micromegaly”: an update on the prevalence of acromegaly with apparently normal GH secretion in the modern era

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• 作者：Laura B. Butz ; Stephen E. Sullivan ; William F. Chandler ; Ariel L. Barkan
• 关键词：Acromegaly ; Pituitary tumor ; Insulin ; like growth factor 1 ; Growth hormone
• 刊名：Pituitary
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：19
• 期：6
• 页码：547-551
• 全文大小：370 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Diabetes
  Neurosurgery
  
• 出版者：Springer Netherlands
• ISSN：1573-7403
• 卷排序：19

文摘

PurposeApproximately 25 % of cases of clinically active acromegaly cases treated in our academic center between 1996 and 2000, were diagnosed in patients who had elevated plasma IGF-1 levels, but apparently “normal” 24-h mean plasma GH levels. The current study served to update the data for patients with acromegaly referred to our facility, after increasing awareness of this “normal” GH subpopulation throughout the medical community.