Quality evaluation of Perillae Folium by HPLC/PDA

详细信息    查看全文

• 作者：Bing Tian Zhao ; Kang Ro Lee ; Je Hyun Lee ; Byung Sun Min…
• 关键词：Perillae Folium ; Lamiaceae ; Quantitation ; HPLC
• 刊名：Archives of Pharmacal Research
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：38
• 期：8
• 页码：1521-1529
• 全文大小：633 KB
• 参考文献：Chen, J.H., Z.H. Xia, and R.X. Tan. 2003. High performance liquid chromatographic analysis of bioactive triterpenes in Perilla frutescens. Journal of Pharmaceutical Biomedical Analysis 32: 1175-179.PubMed View Article
  Farina, C., M. Pinza, and G. Pifferi. 1998. Synthesis and anti-ulcer activity of new derivatives of glycyrrhetic, oleanolic and ursolic acid. Farmaco 53: 22-2.PubMed View Article
  Jang, H.J., J.Y. Park, and Y.T. Kim. 1991. Volatile components of Perillae Folium. Korean Journal of Food Science and Technology 23: 129-32.
  Jeoung, G.H., S.H. Han, and G.J. Kil. 2008. A study of anticoagulation activity from Perillae Folium extract. The Korea Journal of Herbology 23: 191-96.
  Kang, R., R. Helms, M.J. Stout, Z.Q. Chen, and T. Nakatsu. 1992. Antimicrobial activity of the volatile constituents of Perilla frutescens and its synergistic effects with polygodial. Journal of Agricultural and Food Chemistry 40: 2328-330.View Article
  Kim, B.Y., J.S. Jeong, H.J. Kwon, J.H. Lee, and S.P. Hong. 2008. Determination of rosmarinic acid and caffeic acid from Perilla frutescens var. japonica and var. acuta by reversed-phase HPLC. The Korea Journal of Herbology 23: 67-2.View Article
  Korea Food and Drug Administration. 2013. Korean pharmacopoeia part II (K.P. X), 969. Seoul: Shinil Books.
  Lee, Y.J., and C.M. Yang. 2006. Growth behavior and perillaldehyde concentration of primary leaves of Perilla frutescens (L.) Britton grown in different seasons. Crop, Environment & Bioinformatics 3: 135-46.
  Nitta, M., H. Kobayashi, M.O. Kameyama, T. Nagamine, and M. Yoshida. 2006. Essential oil variation of cultivated and wild Perilla analyzed by GC/MS. Biochemcal Systematics and Ecology 34: 25-7.View Article
  Ohk, H.C., and Y.A. Chae. 2004. Analysis of volatile oil components and identification of chemotypes in Jaso (Perilla frutescens) collected in Korea. Korean Journal of Medicinal Crop Science 12: 97-01.
  Son, H.U., J.C. Heo, M.S. Seo, and S.H. Lee. 2010. Effects of perilla frutescens L. on anti-oxidant and anti-inflammation activity. Korean Journal of Food Preservation 17: 757-61.
  Song, L.R., X. Hong, and X.L. Ding. 2001. Modern Chinese materia medica lexicon, 2146. Beijing: People Health Publishing House Press.
  The Minister of Health, Labor and welfare of Japan. 2008. The Japanese Pharmacopoeia 15th Edition (J.P.), 1329-330. Tokyo: The Minister of Health, Labor and Welfare of Japan Press.
  The Pharmacopoeia Commission of the PRC. 2010. Pharmacopoeia of People’s Republic of China (C.P.), 318-19. Beijing: Chemical Industry Press.
  You, H.Y., C.Y. Choi, J.Y. Kim, S.J. Park, K.S. Hahm, and H.G. Jeong. 2001. Ursolic acid enhances nitric oxide and tumor necrosis factor-alpha production via nuclear factor-kappa B activation in the resting macrophages. FEBS Letters 509: 156-60.PubMed View Article
  
• 作者单位：Bing Tian Zhao (1)
  Kang Ro Lee (2)
  Je Hyun Lee (3)
  Byung Sun Min (1)
  Jong Keun Son (4)
  Mi Hee Woo (1)
  
  1. College of Pharmacy, Catholic University of Daegu, Gyeongsan, 712-702, Republic of Korea
  2. College of Pharmacy, SungKyunKwan University, Suwon, 440-736, Republic of Korea
  3. College of Oriental Medicine, Dongguk University, Gyeongju, 780-714, Republic of Korea
  4. College of Pharmacy, Yeungnam University, Gyeongsan, 712-749, Republic of Korea
  
• 刊物主题：Pharmacy; Pharmacology/Toxicology;
• 出版者：Springer Netherlands
• ISSN：1976-3786

文摘

To establish a standard of quality control for Perillae Folium (Lamiaceae Family), four standard compounds including rosmarinic acid, elemicin, perillaldehyde, and dillapiole were evaluated by high-performance liquid chromatography (HPLC)/photodiode array (PDA). The four standards were analyzed with a Phenomenex Kinetex C18 (250?×?4.6?mm, 5?μm) column by gradient elution using 0.1?% formic acid in water and methanol as the mobile phase. The standards were quantified by HPLC/PDA from Perillae Folium, which included the leaf and twig of Perilla frutescens L. Britton var. acuta (Thunb.) Kudo or Perilla frutescens Britton var. crispa Decne. The method was successfully used in the analysis of Perillae Folium, and the linearity, recovery, precision, accuracy, stability, and robustness were satisfactory according to the validation results. In Perillae Folium samples, the average contents (wt%) of rosmarinic acid, elemicin, perillaldehyde, and dillapiole were 0.540, 0.059, 0.050, and 0.056?%, respectively. The results indicate that the established HPLC/PDA method is suitable for the quantitation and quality evaluation of Perillae Folium.