MDI Biological Laboratory Arsenic Summit: Approaches to Limiting Human Exposure to Arsenic

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• 作者：Bruce A. Stanton ; Kathleen Caldwell…
• 关键词：Arsenic ; Rice ; Water ; Drinking water regulations ; Multi ; sector collaborations ; Community outreach ; Education
• 刊名：Current Environmental Health Reports
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：2
• 期：3
• 页码：329-337
• 全文大小：366KB
• 参考文献：Papers of particular interest, published recently, have been highlighted as: 鈥?Of importance1.Blum D. The poisoner鈥檚 handbook: murder and the birth of forensic medicine in Jazz Age New York. New York: Penguin Group (USA) Inc; 2010.
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  4.World Health Organization. Guidelines for drinking-water quality: incorporating first and second addenda to third edition. 2008;1鈥擱ecommendations http://鈥媤ww.鈥媤ho.鈥媔nt/鈥媤ater_鈥媠anitation_鈥媓ealth/鈥媎wq/鈥媑dwq3rev/鈥媏n/鈥?/span> Accessed 12 April 2015.
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  7.鈥?/div>Schmidt CW. In search of 鈥渏ust right鈥? the challenge of regulating arsenic in rice. Environ Health Perspect. 2015;123(1):A16鈥?. doi:10.鈥?289/鈥媏hp.鈥?23-A16 . This paper reviews ongoing discussions to reduce arsenic exposures from rice.PubMed Central PubMed CrossRef
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  15.Shi X, Ayotte JD, Onda A, et al. Geospatial association between adverse birth outcomes and arsenic in groundwater in New Hampshire, USA. Environ Geochem Health. 2015;37(2):333鈥?1. doi:10.鈥?007/鈥媠10653-014-9651-2 .PubMed CrossRef
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  17.鈥?/div>Wasserman GA, Liu X, Loiacono NJ, et al. A cross-sectional study of well water arsenic and child IQ in Maine schoolchildren. Environ Heal Glob Access Sci Source. 2014;13(1):23. doi:10.鈥?186/鈥?476-069X-13-23 . This paper reports that very low levels of arsenic in well water are associated with a reduction in IQ in children in Maine.
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  27.鈥?/div>Zheng Y, Ayotte JD. At the crossroads: hazard assessment and reduction of health risks from arsenic in private well waters of the northeastern United States and Atlantic Canada. Sci Total Environ. 2015;505:1237鈥?7. doi:10.鈥?016/鈥媕.鈥媠citotenv.鈥?014.鈥?0.鈥?89 . This article presents an overview of a special issue of the journal containing 12 papers that present data on arsenic hydrogeochemistry, well water treatment systems, and testing and treatment behaviors of individuals who drink well water.PubMed CrossRef
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  30.Flanagan SV, Marvinney RG, Johnston RA, et al. Dissemination of well water arsenic results to homeowners in Central Maine: influences on mitigation behavior and continued risks for exposure. Sci Total Environ. 2015;505:1282鈥?0. doi:10.鈥?016/鈥媕.鈥媠citotenv.鈥?014.鈥?3.鈥?79 .PubMed CrossRef
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  32.Peters SC, Blum JD, Klaue B, et al. Arsenic occurrence in New Hampshire drinking water. Environ Sci Technol. 1999;33:1328鈥?3.CrossRef
  33.Flanagan SF, Ayotte JD, Robinson Jr GR. Quality of water from crystalline rock aquifers in New England, New Jersey, and New York, 1995鈥?007. Virginia: Reston; 2012.
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  52.Norton GJ, Douglas A, Lahner B, et al. Genome wide association mapping of grain arsenic, copper, molybdenum and zinc in rice (Oryza sativa L.) grown at four international field sites. PLoS One. 2014;9(2):e89685. doi:10.鈥?371/鈥媕ournal.鈥媝one.鈥?089685 .PubMed Central PubMed CrossRef
  53.Hojsak I, Braegger C, Bronsky J, et al. Arsenic in rice: a cause for concern. J Pediatr Gastroenterol Nutr. 2015;60(1):142鈥?. doi:10.鈥?097/鈥婱PG.鈥?000000000000502鈥?/span> .PubMed CrossRef
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  56.Song WY, Yamaki T, Yamaji N, et al. A rice ABC transporter, OsABCC1, reduces arsenic accumulation in the grain. Proc Natl Acad Sci U S A. 2014;111(44):15699鈥?04. doi:10.鈥?073/鈥媝nas.鈥?414968111 .PubMed Central PubMed CrossRef
  57.Consumer Reports. Arsenic In Your Food. 2012 http://鈥媤ww.鈥媍onsumerreports.鈥媜rg/鈥媍ro/鈥媘agazine/鈥?012/鈥?1/鈥媋rsenic-in-your-food/鈥媔ndex.鈥媓tm Accessed 12 April 2015.
  58.Carrington CD, Murray C, Tao S. A quantitative assessment of inorganic arsenic in apple juice: U.S. Food and Drug Administration. 2013 http://鈥媤ww.鈥媐da.鈥媑ov/鈥婩ood/鈥婩oodborneIllness鈥婥ontaminants/鈥婱etals/鈥媢cm280209.鈥媓tm Accessed 12 April 2015.
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  62.Meng XY, Qin J, Wang LH, et al. Arsenic biotransformation and volatilization in transgenic rice. New Phytol. 2011;191(1):49鈥?6. doi:10.鈥?111/鈥媕.鈥?469-8137.鈥?011.鈥?3743.鈥媥 .PubMed Central PubMed CrossRef
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• 作者单位：Bruce A. Stanton (1)
  Kathleen Caldwell (2)
  Clare Bates Congdon (3)
  Jane Disney (4)
  Maria Donahue (5)
  Elizabeth Ferguson (6)
  Elsie Flemings (5)
  Meredith Golden (7)
  Mary Lou Guerinot (8)
  Jay Highman (9)
  Karen James (4)
  Carol Kim (10)
  R. Clark Lantz (11)
  Robert G. Marvinney (12)
  Greg Mayer (13)
  David Miller (14)
  Ana Navas-Acien (15)
  D. Kirk Nordstrom (16)
  Sonia Postema (9)
  Laurie Rardin (17)
  Barry Rosen (18)
  Arup SenGupta (19)
  Joseph Shaw (20)
  Elizabeth Stanton (21)
  Paul Susca (22)
  
  1. Center for the Environmental Health Sciences, Department of Microbiology and Immunology, The Geisel School of Medicine at Dartmouth, Hanover, NH, 03755, USA
  2. Centers for Disease Control and Prevention, National Center for Environmental Health, Atlanta, GA, USA
  3. Maine Medical Center Research Institute, 81 Research Dr, Scarborough, ME, 04074, USA
  4. Mt. Desert Island Biological Laboratory, Salisbury Cove, ME, 40672, USA
  5. Healthy Acadia, 140 State Street, Ellsworth, ME, 04605, USA
  6. Engineer Research and Development Center, US Army Corp of Engineers, 3909 Halls Ferry Road, Vicksburg, MS, 39180-6199, USA
  7. Columbia University Earth Institute, 61 Route 9W, PO Box 1000, Palisades, NY, 10964-8000, USA
  8. Center for the Environmental Health Sciences, Department of Biological Sciences, Dartmouth College, Hanover, NH, 03755, USA
  9. Nature鈥檚 One, Inc., 8754 Cotter Street, Lewis Center, OH, 43035, USA
  10. Department of Molecular & Biomedical Sciences, University of Maine, Orono, ME, 04469, USA
  11. Department of Pharmacology and Toxicology, The University of Arizona, Tucson, AZ, 85724-5044, USA
  12. Maine Geological Survey, 93 State House Station, Augusta, ME, 04333, USA
  13. Department of Environmental Toxicology, Texas Tech University, Lubbock, TX, 79409, USA
  14. Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, 111 T.W. Alexander Drive, Research Triangle Park, Chapel Hill, NC, 27709, USA
  15. Environmental Health Sciences, Johns Hopkins University, Baltimore, MD, 21205, USA
  16. United States Geological Survey, Boulder, CO, 80303, USA
  17. Center for the Environmental Health Sciences, The Geisel School of Medicine at Dartmouth, Hanover, NH, 03755, USA
  18. Department of Biochemistry and Molecular Biology, Florida International University, Miami, FL, 33199, USA
  19. Environmental Engineering, Lehigh University, 1 West Packer Avenue, Bethlehem, PA, 18015, USA
  20. School of Public and Environmental Affairs, University of Indiana, 1315 East Tenth Street, Bloomington, IN, 47405, USA
  21. Risk Management, Dartmouth Hitchcock Medical Center, Lebanon, NH, 03756, USA
  22. NH Department of Environmental Services, 29 Hazen Drive, PO Box 95, Concord, NH, 03302, USA
  
• 刊物类别：Pharmacology/Toxicology; Medicine/Public Health, general; Environmental Health;
• 刊物主题：Pharmacology/Toxicology; Medicine/Public Health, general; Environmental Health;
• 出版者：Springer International Publishing
• ISSN：2196-5412

文摘

This report is the outcome of the meeting 鈥淓nvironmental and Human Health Consequences of Arsenic鈥?held at the MDI Biological Laboratory in Salisbury Cove, Maine, August 13鈥?5, 2014. Human exposure to arsenic represents a significant health problem worldwide that requires immediate attention according to the World Health Organization (WHO). One billion people are exposed to arsenic in food, and more than 200 million people ingest arsenic via drinking water at concentrations greater than international standards. Although the US Environmental Protection Agency (EPA) has set a limit of 10 渭g/L in public water supplies and the WHO has recommended an upper limit of 10 渭g/L, recent studies indicate that these limits are not protective enough. In addition, there are currently few standards for arsenic in food. Those who participated in the Summit support citizens, scientists, policymakers, industry, and educators at the local, state, national, and international levels to (1) establish science-based evidence for setting standards at the local, state, national, and global levels for arsenic in water and food; (2) work with government agencies to set regulations for arsenic in water and food, to establish and strengthen non-regulatory programs, and to strengthen collaboration among government agencies, NGOs, academia, the private sector, industry, and others; (3) develop novel and cost-effective technologies for identification and reduction of exposure to arsenic in water; (4) develop novel and cost-effective approaches to reduce arsenic exposure in juice, rice, and other relevant foods; and (5) develop an Arsenic Education Plan to guide the development of science curricula as well as community outreach and education programs that serve to inform students and consumers about arsenic exposure and engage them in well water testing and development of remediation strategies. Keywords Arsenic Rice Water Drinking water regulations Multi-sector collaborations Community outreach Education